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The mortality rate of coronavirus disease-19 (COVID-19) has been reported as 1–6% in most studies. The cause of most deaths has been acute pneumonia. Nevertheless, it has been noted that cardiovascular failure can also lead to death. Three COVID-19 patients were diagnosed based on reverse transcriptase-polymerase chain reaction of a nasopharyngeal swab test and radiological examinations in our hospital. The patients received medications at the discretion of the treating physician. In this case series, chest computed tomography scans and electrocardiograms, along with other diagnostic tests were used to evaluate these individuals. Sudden cardiac death in COVID-19 patients is not common, but it is a major concern. So, it is recommended to monitor cardiac condition in selected patients with COVID-19.

Introduction A novel coronavirus named severe acute respiratory syndrome coronavirus 2, was first reported in Wuhan, China, in December 2019. The virus, known as COVID-19, is recognized as a potentially life-threatening disease by causing severe respiratory disease. Since this virus has not previously been detected in humans, there is a paucity of information regarding its effects on humans. In addition, only limited or no information exists about its impact during pregnancy. Case presentation In the present case study, we report the death of a neonate born to a 32-year-old mother with coronavirus disease 2019 in Ilam, Iran, with Kurdish ethnicity. We report the infection and death of a neonate in Iran with a chest X-ray (CXR) marked abnormality 2 hours after birth demonstrating coronavirus disease 2019 disease. The neonate was born by elective cesarean section, the fetal health was assessed using fetal heart rate and a non-stress test before the birth, and there was no evidence of fetal distress. All the above-mentioned facts and radiographic abnormalities suggested that coronavirus disease 2019 is involved. Conclusions In this case study, we report the death of a neonate born to a mother with coronavirus disease 2019, 11 hours after birth. There is a paucity of data on the vertical transmission and the adverse maternal-fetal consequences of this disease, so vertical transmission from mother to child remains to be confirmed.

Context: Acetylcysteine is an effective treatment for acetaminophen poisoning. The preparation and dose calculation of acetylcysteine is associated with medical errors. The prevalence of this error is 84.3% globally. Case report: A 15-year-old girl took an overdose of acetaminophen in a suicide attempt. Acetylcysteine intravenous was ordered. Due to the medication error by the nurse, she received a 10-fold overdose of intravenous acetylcysteine in both initial loading dose and maintenance dose. On the second day, the patient showed abdominal pain, nausea, vomiting, and elevated liver enzymes. Her hemoglobin, hematocrit, and platelet quickly decreased. Subsequently, she developed oliguria, anuria, and rising serum creatinine levels. The patient was diagnosed with uremic hemolytic syndrome. She underwent hemodialysis and was treated with plasmapheresis, blood transfusions, and platelets. Discussion: The effects of acetaminophen poisoning and acetylcysteine overdose may be much more severe and have a greater impact on patient survival. Timely and accurate treatment measures can help prevent long-term side effects.

Objectives: This study was conducted to evaluate the clinical features of 68 coronavirus 2019-infected cardiac cases on gender basis. Methodology: Clinical, laboratory and electrocardiographic data of 68 COVID-19 patients with pre-existing cardiovascular diseases, analyzed and compared by gender-wise. Results: Dry cough (78% of male, 80% females) and fever (62% of male, 75% females) were the most common symptoms. Out of these 97% of them needed O2 supplementation. O2 saturation in patients with O2 therapy was 85%; 31% of men and 11% of women experienced intubation. The most common laboratory abnormalities, were neutrophilia, leukocytosis, lymphopenia, thrombocytopenia, decreased hemoglobin level, increased creatinine and urea, in men and women. Troponin level was different between male and female. Pneumonia was found in 86-87% patients. Approximately, Males and female, respectively53.10 and 52.8%, shown sinus tachycardia (ST arrythmia). PVC arrythmia was found in 2.9% of total patients. BBB arrythmia was found in 31.20% of males vs. 11.10% of females. The mean systole/diastole blood pressures respectively were 130±4/79.7 ±2 in males and 134±4/81±3 in females. Heart axis changes was identified in 43.8% and 27.8% of males and females respectively. Conclusion: Severity of symptoms and outcomes of COVID-19 in cardiac patients showed some differences between men and women which could be associated with differences in immune responses, respiratory tract properties, renin angiotensin system, sex hormones and lifestyle.  However, more studies to categorize gender differences are required.

Given the importance of relieving pain and disability experienced by the patients, the present study aimed to study the Effects of topical olive oil on the pain intensity among patients with knee osteoarthritis. The patients were randomly assigned into the experimental (28 patients) and control groups (27 patients). Firstly, in tropical olive oil (TOO) group, a high-quality olive oil, branded as Famila was used and in the control group, Diclofenac gel was applied. In experimental groups, 5 drops of herbal oils were applied to the knee thrice a day at morning, noon and evening and the knees were covered with a nylon sheet for more absorption. The patients were followed up for 4 weeks and their capability and pain intensities were evaluated prior the study, during the first week, the second week and the fourth week with Visual Analogue Scale. Data were analyzed using descriptive and analytical tests by SPSS V. 16 software. According to the findings, also the Mean (SD) pre-intervention Pain score in experimental group A was 8.10(0.91), which decreased to 1.78(0.78) after the intervention and in the control group from 8.55(0.69) to 3.85(0.98). Due to the greater effect of olive oil compared to Diclofenac gel on reducing pain of patients with KOA, it is recommended that patients use olive oil. Further studies are also recommended.

Introduction: COVID-19 has caused a great deal of fear indifferent communities. In this study, we reported the recovery of a diabetic elderly woman with a history of asthmafromCOVID-19 infection. Case Presentation: A 61-year-old woman was hospitalized due to dyspnea and low blood O2 saturation and later diagnosed with COVID-19, as confirmed by PCR. The patient had a history of asthma and diabetes and used salbutamol and Atrovent spray. She also had a history of hospitalization at one month prior to the current admission. Despite all these, COVID-19was successfully managed, and she was discharged with a good clinical condition after the improvement of respiratory complications. Conclusion: Despite having an advanced age and underlying diseases (diabetes and asthma), the recovery of this elderly woman shows that even such patientscandefeatCOVID-19 as long as the disease is not progressed to advanced phases and appropriate therapeutic measures are taken. By reporting such cases, it is possible to give people hope and motivation and reduce their fear of the disease.

The novel corona virus has infected about 141 million people around the world. So far, about 80.4 million people have been discharged, and nearly 3.01 million people have died (an estimated mortality rate of 2.13%). The study aimed to investigate the effect of plasma therapy from recovered Covid-19 patients to treat the patients hospitalized in the intensive care unit (ICU) of the Shahid Mostafa Khomeini Hospital of Ilam in 2020. The present prospective study was conducted in 2019-2020.Overall, 57 cases of plasma therapy were analyzed using the Cox proportional hazard regression model in STATA 12 software. The results showed in patients receiving plasma treatment, the hazard ratio of was (HR=0.68, 95% CI, 0.45-1.04), indicating a 32% lower risk of death in the Covid-19 patients who received plasma therapy compared to those who did not. However, this relationship does not reach statistical significance (p =0.07). Plasma therapy seems to yield some efficacy among patients with severe COVID-19and those who have no underlying diseases. It is recommended to be used in combination with pharmaceutical interventions, for example Actemra, to assess its therapeutic efficiency.