BACKGROUND: Liver dysfunction is associated with protean manifestations in skin, nails and hairs. OBJECTIVE: To study cutaneous manifestations in liver diseases. METHODS & MATERIALS: The patients of liver disease of any etiology and either sex, from January 2010 to
Objective: The main aim of the study was to screen the isolated compounds of Viburnum Punctatum for its in vitro anticancer activity and its percentage viability against HCT 15 (Human Colon Cancer Cells) Cell lines.Methods: Pet ether, Chloroform, Methanol and Aqueous extracts was prepared and assayed for the presence of phytochemicals. Two compounds were isolated from the methanol extract of Viburnum Punctatum by column chromatography such as ME1 (Quercetin) and ME2 (Kaemferol-3-glycoside) characterised by UV, IR, MS, 1 H NMR and 13Results: ME1 showed significant cytotoxic activity than the ME2 on HCT 15 cells with a percentage viability of 54.60 and 67.18 in the concentration of 10µg/ml and 50µg/ml respectively. C NMR. The above isolated compounds were subjected to in vitro anticancer activity on HCT 15 cell lines was evaluated by Micro culture Tetrazolium (MTT) assay.
Conclusion:On the basis of obtained results, ME1 and ME2 isolated from a methanolic extract of Viburnum Punctatum represent a new group of cytotoxic against HCT 15 Cell lines.
This study intended to assess effectiveness of conflict resolution strategies in a public secondary schools’ management in Morogoro Municipality. The study employed a descriptive research design based on mixed research approach. Both purposive and random sampling techniques were used in selecting study area and 112 respondents from 7 public secondary schools in Morogoro municipality. Questionnaires and interviews were research instruments used to collect data. Also, the collected data were descriptively analyzed to generate the frequencies and percentages with the help of SPSS software version 25. The study results showed that conflict resolution strategies have positive impact on the effectiveness management by ensuring peace and harmony, high job performance, high academic performance, the spirit of teamwork, high retention of teachers and problem-solving. Based on the study findings, a researcher recommended that the school administrator should involve teachers in conflict management methods to allow for the creation of good and constructive relationships.
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