A Clinical Study of Cutaneous Manifestations in Liver Diseases

Gavli, Jai; Dubey, Anand Kumar; Alex, A. Renjith; Jain, Rajesh

doi:10.14260/jemds/1332

Cited by 2 publications

(20 citation statements)

References 5 publications

(4 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These manifestation occured in all types of liver diseases, the most common being cholestatic (100%), followed by hepatitis B infections (87.5%), Wilson's disease (75%), hepatosellular carcinoma (75%), hepatitis C infections (71.43%), alcoholic liver disease (50%). 12 Pruritus was the second most common manifestation in our study, which was 50% of cases. Similar studies by Gavli et al reported pruritus in 45% cases, Choudhury et al reported pruritus in 27% cases, and Kochhar et al reported pruritus in 92% cases as the most common symptom.…”

Section: Resultsmentioning

confidence: 47%

“…11 The high prevalence of male patients was attributed to greater access to health services centers. 12 The most common etiology of chronic liver disease in our study was chronic hepatitis B infections (45.2%), followed by liver cirrhosis (38.1%), and chronic hepatitis C infections (16.7%). A similar study by Gavli et al in India reported the most common etiology was hepatitis B (32%), followed by alcoholic liver disease (26%), hepatitis C (14%), cholestatic liver disease (8%), hepatocellular carcinoma (6%), Wilson disease (4%), and autoimmune disease (2%).…”

Section: Resultsmentioning

confidence: 61%

“…A similar study by Gavli et al in India reported the most common etiology was hepatitis B (32%), followed by alcoholic liver disease (26%), hepatitis C (14%), cholestatic liver disease (8%), hepatocellular carcinoma (6%), Wilson disease (4%), and autoimmune disease (2%). 12 Study by Khan et al reported different things in Pakistan, where out of 50 patients, most common etiology was chronic hepatitis C infections (60%), followed by chronic hepatitis B infections (28%), cirrhosis primary biliary and Wilson's disease (4%). 5 While study by Godara et al in India, reported most common etiology was malignancies (18.4%), followed by non-alcoholic steatohepatitis (18.2%), cholelithiasis (15.8%), and cirrhosis (13.9%).…”

Section: Resultsmentioning

confidence: 98%

“…1 The high incidence of hepatitis B and C is associated with the increased availability of serological examinations, screening for viral markers in liver involvements, blood transfusions, and surgical procedures. 12 In Indonesia, the proportion of patients with liver cirrhosis is most often caused by hepatitis B virus infections, alcoholic liver disease, and hepatitis C virus infections so that these etiologies of chronic liver disease were the most common. 13 Among the various types of cutaneous manifestations in our study, xerosis was the most frequent skin lesion (95.2%), where this finding was higher than other similar studies.…”

Section: Resultsmentioning

confidence: 99%

“…Similar studies by Gavli et al and Choudhury et al reported xerosis was 78% and 62%, respectively. 11,12 Xerosis is the most common manifestation of liver dysfunction caused by prolonged nature of disease and decompensation, with malnutrition. This condition is also caused by an increase in transepidermal water loss and a decrease in skin hydration associated with ceramide and type I collagen degradation.…”

Section: Resultsmentioning

confidence: 99%

See 4 more Smart Citations

Profile of Cutaneous Manifestations in Chronic Liver Disease in H. Adam Malik General Hospital Medan

Chandra¹,

Roesyanto-Mahadi²,

Yosi³

2019

IJSRP

View full text Add to dashboard Cite

Introduction: Chronic liver disease (CLD), caused by occurrence of abnormalities that occur continuously without healing in at least six-months. Among all extrahepatic manifestations of liver disease, skin manifestations are the most common. Objective: To determine the description of skin disorders in CLD. Methods: A descriptive study involving subjects with CLD (especially chronic hepatitis-B, chronic hepatitis-C, and liver cirrhosis) that attending to internal department of H.Adam Malik General Hospital Medan during October 2018. Skin disorders were diagnosed through history taking and clinical examination. Results: Out of 42 subjects, highest proportion was male (71,4%) and highest distribution in age group of 46-55 years (30,95%). The most common causes of CLD were chronic hepatitis-B (45,2%), followed by liver cirrhosis (38,1%), and chronic hepatitis-C (16,7%). The most common cutaneous manifestations were xerosis (95,2%), pruritus (50%), and gutate hypopigmentation (33,3%). Other cutaneous manifestations included spider angioma (30,95%), hyperpigmentation (23,8%), tinea versicolor (21,4%), palpable purpura and folliculitis (16,7%), dilated abdominal veins and paper money skin (14,3%), jaundice (9,5%), prurigo of hebra and miliaria rubra (4,76%), and most rarely were lichen simplex chronicus, vitiligo, and palmar erythema (2,38%). Most subjects in this study had more than one cutaneous manifestations. Conclusion: CLD can give a wide spectrum of cutaneous manifestations, included xerosis, pruritus, pigmentary changes, vascular changes, jaundice, and infections. This manifestations give a strong correlation between skin and liver disease, that can be a clue to the presence of underlying liver disease.

show abstract

Section: Resultsmentioning

confidence: 47%

Section: Resultsmentioning

confidence: 61%

Section: Resultsmentioning

confidence: 98%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations