Organometallic compounds conjugates play a vital role in new drug discovery, in which Schiff base is useful as a ligand in consideration with different metals. Schiff base mostly encouraged due to its versatile activity due to the presence of a unique Imine (C=N) group. An attempt has been taken to synthesize a Schiff base by using salicylaldehyde and ethylene diamine which further design for the incorporation of salts of Cu, Ni and Zn metals separately. The ligand and its metal complexes have been carried out several characterization studies like elemental analysis, molar conductance, UV, IR and H 1 NMR. DPPH antioxidant potential and antimicrobial effect against four species Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli, and Staphylococcus aureus have been done with the ligand and all its metal complexes. The result revealed that metal incorporation in the Schiff base ligand enhanced the antioxidant potential as well as remarkable antimicrobial effect.
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