Background: The study of processes in the drying drops of biological fluids (dried drop patterns) and the method of dynamic surface tensiometry can be attributed to integral methods of assessing the state of the organism. Research objective: to establish the relationship between the type of crystallization patterns and the surface tension of human saliva in normal conditions. Methods: 100 volunteers (40 males, 60 females) that were aged 30–59 participated in the study. In all saliva samples, the parameters of dynamic tensiometry, types of crystallization patterns and 11 biochemical parameters were determined. Results: No statistically significant differences in the saliva crystallization patterns were observed, depending on the age and gender characteristics of the volunteers. A negative correlation of the area of the crystallization zone and the surface tension of saliva is shown. When considering the crystallization patterns, their considerable variability was noted; on this basis, the entire studied sample was divided into four clusters by surface tension. Conclusion: In general, the crystallization patterns that are inside the selected groups remain quite heterogeneous. This increases the likelihood of making an incorrect diagnosis when using visual methods to evaluate the crystallization patterns, which significantly limits the use of such diagnostic methods in clinical practice.

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Creation of osteoinductive materials based on biocompatible synthetic salts, with a sufficiently high strength and porosity, with the shape which allow filling bone defects with various shapes and sizes is an actual task of modern biomaterial science. In this work, a series of granular materials were obtained from synthetic powders with various proportions of hydroxyapatite and wollastonite using a suspension technology based on the principle of immiscible liquids. Ceramic particles have a spherical shape, microhardness at least 17 HV and open porosity about 50 %. These materials can be used for reparation of bone defects of various locations, shapes and sizes in surgical dentistry, traumatology and orthopaedics.

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