Aim - analysis of immunological and microbiological indicators of oral cavity in elderly patients who use complete and partial removable dentures. Materials and methods. 42 patients with combinations of complete and partial absence of teeth were involved in the research. The group included 27 women and 15 men, whose age varied from 60 to 74 years. All patients used complete and partial removable dentures. Results. The results show marked abnormality of microbiocenosis of the oral mucosa in patients engaged in the research. Conclusion. The results of the microbiological research of the oral mucosa in elderly patients who use removable dentures demonstrate significant dysbiotic changes in the resident and transient oral microflora both in quantitative and qualitative indicators.
доктор медицинских наук, профессор кафедры клинической медицины последипломного образования, Медицинский университет «Реавиз», Самара, Россия ORCID 0000-0002-9448-8232
Монаков Вячеслав Александровичкандидат медицинских наук, ассистент кафедры челюстно-лицевой хирургии и стоматологии, Самарский государственный медицинский университет, Самара, Россия ORCID 0000-0001-5522-0420
Нестеров Александр Михайловичдоктор медицинских наук, профессор кафедры ортопедической стоматологии, Самарский государственный медицинский университет, Самара, Россия ORCID 0000-0001-7970-4913
Relevance. The most important condition for a successful result of dental implantation is high-quality osseointegration of dental implants. In the literature, the issue of the quality of osseointegration is widely covered, which directly depends on the primary stability of dental implants. In the area of bone tissue remodeling, surrounding the installed dental implants, there are permanent processes of bone resorption and its restoration [1][2].The aim is to reveal the reactivity of alkaline phosphatase and osteocalcin in the biological fluid (saliva) in patients after dental implants.Materials and methods. The collection and analysis of clinical material was carried out on the basis of the Clinics of the Samara State Medical University of the Ministry of Health of Russia. Dental implantation surgery was performed in 184 patients aged 32 to 65 years. The gender ratio was 2:3 (40 men and 60 women). The teeth were lost due to poor oral hygiene and caries complications.Results and discussion. At the time of admission of patients to the department of the Department of Prosthetic Dentistry of the Clinics of the Samara State Medical University of the Ministry of Health of Russia, the bulk of the patients had a low hygienic status. The OHI-S index averaged 2.74 ± 0.33 conventional units. (control – 0.50 ± 0.07 c.u.). In order to reduce the negative influence of microorganisms in the supra- and subgingival dental deposits, all patients underwent professional oral hygiene, as well as antimicrobial therapy. At the time of installation of dental implants, the average OHI-S and Müllemann-Cowell index was 0.72 ± 0.06 and 0.57 ± 0.06 conventional units, respectively.Conclusions. 1. The increase in the titer of alkaline phosphatase and osteocalcin during dental implantation is not statistically significant. 2. TCRF in the oral fluid (saliva) exhibits maximum activity by the 14th day, exceeding the initial three times. This indicator remains at an increased level in the period up to six months from the beginning of the operation. 3. Revealing the values of the TRKF titer after the operation of dental implantation is advisable to use as an assessment of the state of trophic processes occurring in the bone tissue.
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