a-[5-( 2-Furyl)-l,3,4-oxadiazol-2-ylthio]acetohydrazide, 4-allyl-1-([5-(2-furyl)-l,3.4-oxadiazol-2-ylthio]acetyl)thiosemicarbazide, and related compounds have been prepared. a-[5-(2-Furyl)-l,3,4-oxadiazol-2-ylthio] acetohydrazide showed in vitro activity against M. tuberculosis.NUMEROUS oxadiazoles are known which possess biological activity. For example, 5-phenyl-l,3,4-oxadiazole-2-thiol is antitubercular and 5-(3-pyridyl)-l,3,4oxadiazole-2-thiol is both leprost at ic and tuberculos t atic,, while 2-(5-nitro-2-furyl)-1,3,4-oxadiazole and other related compounds are active against several pathogenic
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