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An IAEA coordinated research project that began in 2012 and ended in 2016 was primarily dedicated to the compilation, evaluation and recommendation of cross-section data for the production of medical radionuclides. One significant part of this work focused on diagnostic positron emitters. These particular studies consist of 69 reactions for direct and indirect or generator production of 44 Sc(44 Ti), 52m Mn(52 Fe), 52g Mn, 55 Co, 61 Cu, 62 Cu(62 Zn), 66 Ga, 68 Ga(68 Ge), 72 As(72 Se), 73 Se, 76 Br, 82 Rb(82 Sr), 82m Rb, 86 Y, 89 Zr, 90 Nb, 94m Tc, 110m In(110 Sn), 118 Sb(118 Te), 120 I, 122 I(122 Xe), 128 Cs(128 Ba), and 140 Pr(140 Nd) medical radionuclides. The resulting reference cross-section data were obtained from Padé fits to selected and corrected experimental data, and integral thick target yields were subsequently deduced. Uncertainties in the fitted results were estimated via a Padé least-squares method with the addition of a 4% assessed systematic uncertainty. Experimental data were also compared with theoretical predictions available from the TENDL-2015 and TENDL-2017 libraries. All of the numerical reference cross-section data with their corresponding uncertainties and deduced integral thick target yields are available on-line at the IAEA-NDS medical portal www-nds.iaea.org/medic alpor tal and also at the IAEA-NDS web page www-nds.iaea.org/ medic al/posit ron_emitt ers.html.

An extensive series of evaluations have been performed as part of an IAEA coordinated research project to study a set of nuclear reactions that produce the diagnostic gamma-ray emitting radionuclides 51 Cr, 99m Tc, 111 In, 123 I and 201 Tl. Recommended cross-section data in the form of excitation functions have been derived, along with quantifications of their uncertainties. These evaluations involved the compilation of all previously published values and newly measured experimental data, followed by critical assessments and selection of those experimental datasets and accompanying uncertainties judged to be fully valid and statistically consistent for model-independent least-squares fitting by means of Padé approximations. Integral yields as a function of the energy were also calculated on the basis of the recommended cross sections deduced from these various fits. All evaluated numerical results and their corresponding uncertainties are available online at www-nds.iaea.org/medical/gamma_emitters.html and also on the medical portal of the International Atomic Energy Agency/Nuclear Data Section (IAEA-NDS) www-nds.iaea.org/medportal/.

Increasing interest in the treatment of human disease using targeted radionuclide-based therapies requires accurate understanding of achievable radionuclide yield and purity. In the frame of a larger International Atomic Energy Agency Coordinated Research Proposal (IAEA CRP), thirteen nuclear reactions leading to the formation of 131 Cs, 178 Ta, 225 Ra, 225 Ac, 227 Th, and 230 U have been evaluated using all available measured data. Selected datasets have been fit using least-squares method with Padé approximations of variable order, enabling the assignment of energy differential uncertainties to the recommended fit. In some instances, new measurements have been made and reported data has been adjusted to accommodate new nuclear decay or monitor reaction data which adversely altered original reported quantities. In many additional cases, insufficient measured data are available to permit a reliable evaluation of cross sections; these instances are discussed. Recommended therapeutic radionuclide production reaction data and their uncertainties are available on the Web page of the IAEA NDS at www-nds.iaea.org/radionuclides/ and also at the IAEA medical portal www-nds.iaea.org/medportal/ .

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