An ultrastructural study of a metastatic Kaposi's sarcoma in a cervical lymph node demonstrated the presence of endothelial cells, smooth muscle cells, fibroblasts and myofibroblasts. Some of these cells exhibited phagocytic activity in relation to extravasated red blood cells. The ultrastructural features favour the suggestion of an origin of Kaposi's sarcoma from pluripotential mesenchymal cells which may differentiate into more specialised cell types including endothelial, smooth muscle, fibroblastic and myofibroblastic cells.
A case of giant condyloma of Buschke and Loewenstein is presented. The clinical course and pathology of these tumors are reviewed. This case illustrates the delay in establishing the diagnosis in spite of numerous biopsies. It is emphasized that the only effective treatment is wide local excision.
Buschke-Lowenstein tumors are very large, fungating masses usually in the perineal region and are associated with Human Papilloma Virus (HPV). There have been many cases of large masses requiring excision, but on our literature review we were not able to find any that underwent partial closure with a scrotal advancement flap.
from which is derived etiology, is compounded of \ g=a\ \ g=i \ \ g=t \ \ g=i \ \ g=a\ a cause and \ g=l \ \ g=o\ \ g=g\ \ g=o\ \ g=f s\ , which taken in composition signifies a study or science. The whole means the study or science of causes. A\ g=i \ \ g=t \ \ g=i \ \ g=o\ \ g=l \ \ g=o\ \ g=g\ \ g=i \ \ g=kschr \ \ g=f s\ , from which comes etiologic, means a person skilled in the study of causes, and may mean any person or thing pertaining to the science of causation. Factor is a Latin word lugged in to mix with the Greek, and signifies a person doing or producing anything. It has also a mathematical use. When two quantities are multiplied together and bring out a product, they are called factors, that is producers. Putting it all together, an "etiologic factor" should be some person or thing producing some other person or thing skilled in, or related to the science of causes ; or in other words a causative-science-maker ; or a maker of something or of somebody pertaining to the science of causes.
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