β-Cyclodextrin hydrogels as potential drug delivery systems

Cyclodextrin/dextran based hydrogels prepared by cross-linking with sodium trimetaphosphate

“…LC values also increase regularly with the ␤CD content and correspond to a Bzo occupancy rate of the ␤CD cavities around 50-65%. This estimate is in agreement with the results reported in the literature for ␤CD-based hydrogels where LC of ␤CD complexing agents are found to stand in a wide range, comprised between 0.2 and 18%, but are mainly controlled by the ␤CD content of the hydrogels (Cesteros et al, 2009;Glisoni et al, 2013;Hamcerencu et al, 2009;Machín et al, 2012;Rodriguez-Tenreiro et al, 2007;Thatiparti et al, 2010;Xu et al, 2010;Zhang et al, 2013). Fig.…”

“…Taking advantage of the chemical CD structure with many hydroxyl groups, different authors have reported synthesis of hydrogels using ␤CD as a cross-linker with poly(acrylic acid) (Kutyła et al, 2013) or ␤CD-based hydrogels using different crosslinkers such as epichlorohydrin (Machín, Isasi, & Vélaz, 2012;Zhang, Zhou, & Zhang, 2013), ethyleneglycol diglycidyl ether (Glisoni et al, 2013;Rodriguez-Tenreiro, Alvarez-Lorenzo, Rodriguez-Perez, Concheiro, & Torres-Labandeira, 2007), disubstituted poly(ethyleneglycol) (Cesteros, González-Teresa, & Katime, 2009), hexamethylenediisocyanate (Thatiparti, Shoffstall, & von Synthesis conditions and characterization of the hydrogels after purification and freeze-drying (P/O and P/C atomic ratios determined by XPS, and swelling ratio SR determined in pure water).…”

Electrospun Thermoplastic Polyurethane Mats Containing Naproxen– Cyclodextrin Inclusion Complex

“…A Tukey post hoc test revealed that the mean diameter of the TPU nanofibres was statistically significantly higher after loading NAP/β-CD (879.68 ± 159.12 nm, p = 0.000) or NAP/HP-β-CD (834.34 ± 215.37 nm, p = 0.016) inclusion complexes compared with the pure NAP loading (723.50 ± 212.32 nm). There were no statistically significant differences observed in region of 800-2000 cm −1 includes peaks at 1729, indicating the -C=O (carbonyl) stretch, peak at 1630 cm −1 due to ʋ(C-C) modes of the aromatic groups [6] and the peak at 1228 cm -1 , indicative of the -O-stretch [9,11,17] and 1394 cm −1 due to CH 3 bending [10]. The vibration modes detected at 1026 and 857 cm −1 correspond to C-O-C bonds in NAP [27].…”

β-Cyclodextrins as Encapsulating Agents of Essential Oils

“…The use of cyclodextrins is verified in diverse industrial products, such as pharmaceuticals [107,111,112], agrochemicals [113][114][115], and foods [116][117][118][119]. In the food area, cyclodextrins are nontoxic and considered GRAS, and thus are used for several purposes [120,121].…”