Zwitterionic phthalocyanine zinc (II) synthesis, and photodynamic activity comparison with nonionic and cationic phthalocyanine

Gui, Li; Zhang, Quanquan; Wang, Yue; Fang, Kelong; Wang, Ao; You, Xiaoqing; Zhou, Lin; Zhou, Jiahong; Wei, Shaohua

doi:10.1016/j.inoche.2016.11.007

Cited by 10 publications

(1 citation statement)

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“…to the hydrophilic macrocycle ,. A literature survey reveals that there are numerous publications about tetra‐ or octa‐substituted phthalocyanines at peripheral positions having water‐soluble groups . In particular, unknown metallophthalocyanines having a non‐symmetric arrangement with an A 3 B substitution pattern, featuring the common presence of non‐ionic and cationic groups, are synthesized by our group for the first time.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Biological Uses of A₃B Type Water‐Soluble Phthalocyanine Alternate to Alcian Blue

et al. 2018

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This study describes the synthesis and characterization of new non-symmetric cationic phthalocyanine derivatives and their capability for use in staining of microscopic normal and pathological tissue sections, polyacrylamide gel staining, and spectrophotometric analyses. These new synthesized compounds have specifically stained the glycosaminoglycans (GAGs) in the matrix of cartilage tissue of the trachea. In addition, the mucus produced by the stomach, the small intestine and the colon tissue were stained with non-symmetrical cationic phthalocyanines comparable to the Alcian Blue 8GX. In addition, the determination of GAGs and glycoproteins in polyacrylamide gels has also been evaluated. Besides, the usage of these compounds to spectrophotometrically measure GAGs in biological fluids was also investigated. We have found that 6 and 7 are good alternatives to Alcian Blue 8GX due to comparable staining performance and interaction with biological molecules, especially acidic components such as acidic GAGs and mucin. These dyes have good solubility with quaternary ammonium groups effecting their binding performance to biological molecules.

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Section: Introductionmentioning

confidence: 99%

Synthesis and Biological Uses of A₃B Type Water‐Soluble Phthalocyanine Alternate to Alcian Blue

et al. 2018

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Phthalocyanines as medicinal photosensitizers: Developments in the last five years

Zheng

Peng

et al. 2019

Coordination Chemistry Reviews

399

201

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Zinc coordination complexes as anticancer agents

Pellei

Bello

Porchia

et al. 2021

Coordination Chemistry Reviews

125

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Zwitterionic phthalocyanine zinc (II) synthesis, and photodynamic activity comparison with nonionic and cationic phthalocyanine

Cited by 10 publications

References 41 publications

Synthesis and Biological Uses of A₃B Type Water‐Soluble Phthalocyanine Alternate to Alcian Blue

Synthesis and Biological Uses of A₃B Type Water‐Soluble Phthalocyanine Alternate to Alcian Blue

Phthalocyanines as medicinal photosensitizers: Developments in the last five years

Zinc coordination complexes as anticancer agents

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Zwitterionic phthalocyanine zinc (II) synthesis, and photodynamic activity comparison with nonionic and cationic phthalocyanine

Cited by 10 publications

References 41 publications

Synthesis and Biological Uses of A3B Type Water‐Soluble Phthalocyanine Alternate to Alcian Blue

Synthesis and Biological Uses of A3B Type Water‐Soluble Phthalocyanine Alternate to Alcian Blue

Phthalocyanines as medicinal photosensitizers: Developments in the last five years

Zinc coordination complexes as anticancer agents

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Product

Resources

About

Synthesis and Biological Uses of A₃B Type Water‐Soluble Phthalocyanine Alternate to Alcian Blue

Synthesis and Biological Uses of A₃B Type Water‐Soluble Phthalocyanine Alternate to Alcian Blue