Zwitterionic Acetylated Cellulose Nanofibrils

Rostami, Jowan; Mathew, Aji P.; Edlund, Ulrica

doi:10.3390/molecules24173147

Cited by 11 publications

(9 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The acetyl capping of P(B5AMA)-10 post treatment with acetic anhydride was found to be successful by FTIR spectroscopy. cP(B5AMA)-10 showed a characteristic C–O stretch of esters at 1250 cm –1 , bending and stretching of alkanes at 1350 and 2920 cm –1 , respectively, and a CO stretch at 1710 cm –1 . Moreover, the disruption of hydrogen-bonding interaction of the cP(B5AMA)-10 matrix was apparent by the reduced OH group stretching of P(B5AMA)-10 at 3282 cm –1 ; however, the signal intensity of the OH group stretching was stronger than that of dP(B5AMA)-10, suggesting the presence of water molecules in the cP(B5AMA)-10 matrix.…”

Section: Results and Discussionsupporting

confidence: 92%

Elucidating the Role of Thermal Flexibility of Hydrogels in Protein Refolding

Kabir

Ahmed

2020

ACS Appl. Bio Mater.

View full text Add to dashboard Cite

Synthetic chaperones are stimuli-responsive materials that facilitate the refolding of denatured proteins in their native form and release refolded proteins in solution in the presence of external stimuli. Thermoresponsive hydrogels are a class of synthetic chaperones that require heat as an external stimulus to refold the denatured proteins into their biologically active conformations; however, the mechanism by which these hydrogels participate in protein refolding mechanism remains unclear. In this study, we explore the role of physical and structural changes in the hydrogel matrix that may participate in protein refolding efficacies of thermally responsive poly(vitamin B5 analogous methacrylamide) poly(B5AMA) hydrogels. Poly(B5AMA) hydrogels of different net charges, hydrophobicity, and cross-linking densities are synthesized by radical polymerization method and are evaluated for the restoration of enzymatic activity of thermally denatured enzymes (lysozyme and carbonic anhydrase) as a function of temperature and time and for the presence of residual water in the hydrogel architecture. The hydrogels with promising protein renaturation efficacies are further evaluated for their interactions with denatured proteins, and the role of thermal flexibility of the hydrogel matrix in protein refolding capabilities is elucidated.

show abstract

Section: Results and Discussionsupporting

confidence: 92%

Elucidating the Role of Thermal Flexibility of Hydrogels in Protein Refolding

Kabir

Ahmed

2020

ACS Appl. Bio Mater.

View full text Add to dashboard Cite

show abstract

“…The band 1051 cm −1 was assigned to cellulose primary alcohol C-OH stretch [36], a region also assigned to polyphenols from the pure yerba mate extract (1040-1050 cm −1 ) [37]. The cellulose band in this region (dashed lines from Figure 1), was the most prominent one in the cellulose spectra that was not shown when the extract was blended after defibrillation of MFC.…”

Section: Resultsmentioning

confidence: 92%

Yerba Mate Extract in Microfibrillated Cellulose and Corn Starch Films as a Potential Wound Healing Bandage

et al. 2020

View full text Add to dashboard Cite

Microfibrillated cellulose films have been gathering considerable attention due to their high mechanical properties and cheap cost. Additionally, it is possible to include compounds within the fibrillated structure in order to confer desirable properties. Ilex paraguariensis A. St.-Hil, yerba mate leaf extract has been reported to possess a high quantity of caffeoylquinic acids that may be beneficial for other applications instead of its conventional use as a hot beverage. Therefore, we investigate the effect of blending yerba mate extract during and after defibrillation of Eucalyptus sp. bleached kraft paper by ultrafine grinding. Blending the extract during defibrillation increased the mechanical and thermal properties, besides being able to use the whole extract. Afterwards, this material was also investigated with high content loadings of starch and glycerine. The results present that yerba mate extract increases film resistance, and the defibrillated cellulose is able to protect the bioactive compounds from the extract. Additionally, the films present antibacterial activity against two known pathogens S. aureus and E. coli, with high antioxidant activity and increased cell proliferation. This was attributed to the bioactive compounds that presented faster in vitro wound healing, suggesting that microfibrillated cellulose (MFC) films containing extract of yerba mate can be a potential alternative as wound healing bandages.

show abstract

“…Recently, poly(cysteine methacrylate) was surface-grafted on NC by free-radical polymerization, where the coating of this modified NC on the membrane surface yielded excellent antifouling and antibacterial properties . There are other examples of using zwitterionic materials to modify NC, electrospun nanofibers, and CNC, to improve antifouling properties of varying membranes, such as PDVF, and commercial cellulose membranes . The use of zwitterionic polymers to prevent adsorption of proteins is a well-known strategy to reduce fouling, based on the ability of charge-neutral zwitterionic moieties to attract water, forming a hydration layer that thwarts the proteins adsorption (Figure b). − Self-assembled monolayers in Figure c are zwitterionic transplanted from the membrane surface through surface-initiated ATRP reaction by dip coating method or plasmas treatments. , It is known that micro/nanostructured surfaces also can reduce fouling and inactivate bacterial cells by physical means; however, this topic is not included in this review.…”

Section: Nc-enabled Water Purification Technologiesmentioning

confidence: 99%

Nanocellulose for Sustainable Water Purification

et al. 2022

View full text Add to dashboard Cite

Nanocelluloses (NC) are nature-based sustainable biomaterials, which not only possess cellulosic properties but also have the important hallmarks of nanomaterials, such as large surface area, versatile reactive sites or functionalities, and scaffolding stability to host inorganic nanoparticles. This class of nanomaterials offers new opportunities for a broad spectrum of applications for clean water production that were once thought impractical. This Review covers substantial discussions based on evaluative judgments of the recent literature and technical advancements in the fields of coagulation/flocculation, adsorption, photocatalysis, and membrane filtration for water decontamination through proper understanding of fundamental knowledge of NC, such as purity, crystallinity, surface chemistry and charge, suspension rheology, morphology, mechanical properties, and film stability. To supplement these, discussions on low-cost and scalable NC extraction, new characterizations including solution small-angle X-ray scattering evaluation, and structure− property relationships of NC are also reviewed. Identifying knowledge gaps and drawing perspectives could generate guidance to overcome uncertainties associated with the adaptation of NC-enabled water purification technologies. Furthermore, the topics of simultaneous removal of multipollutants disposal and proper handling of post/spent NC are discussed. We believe NC-enabled remediation nanomaterials can be integrated into a broad range of water treatments, greatly improving the cost-effectiveness and sustainability of water purification.

show abstract

Zwitterionic Acetylated Cellulose Nanofibrils

Cited by 11 publications

References 40 publications

Elucidating the Role of Thermal Flexibility of Hydrogels in Protein Refolding

Elucidating the Role of Thermal Flexibility of Hydrogels in Protein Refolding

Yerba Mate Extract in Microfibrillated Cellulose and Corn Starch Films as a Potential Wound Healing Bandage

Nanocellulose for Sustainable Water Purification

Contact Info

Product

Resources

About