Zur Synthese N‐monosubstituierter O‐Acylhydroxylamine. 38. Mitt. über Hydroxylamin‐Derivate

Zinner, G.; Hitze, M.

doi:10.1002/ardp.19693021205

Cited by 7 publications

(2 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Synthesis of the Trimer of 3-tert-Butyl-4,5-dihydropyridazine (10). In a 100-mL flask equipped with N2 atmosphere, condenser, and magnetic stirring was placed 50 mL of benzene and 3.01 g (21.2 mmol) of 4-oxo-5,5-dimethylhexanal.…”

Section: Methodsmentioning

confidence: 99%

4,5-Dihydropyridazines: x-ray structure of a dimer

Dodge¹,

Hedges²,

Timberlake³

et al. 1978

J. Org. Chem.

View full text Add to dashboard Cite

Section: Methodsmentioning

confidence: 99%

4,5-Dihydropyridazines: x-ray structure of a dimer

Dodge¹,

Hedges²,

Timberlake³

et al. 1978

J. Org. Chem.

View full text Add to dashboard Cite

“…The investigation began with the preparation of the reagents, which can be prepared in two steps from N-Boc-N-methyl hydroxylamine (6), 7 by reaction with the appropriate chloroformate under basic reaction conditions followed by removal of the tert-butoxycarbonyl protecting group (Scheme 2). This was found to be a general and reliable method with the methyl 7 (82%), 8 ethyl 8 (73%), benzyl 9 (69%), allyl 10 (79%) and phenyl 11 (73%) reagents being prepared in excellent yield as crystalline solids that were bench stable during the investigation. 9…”

Section: Scheme 1 A-functionalisation Of Carbonyl Compoundsmentioning

confidence: 99%

The Direct Introduction of Carbonates α to Carbonyl Groups

Hall¹,

Jones²,

Jones³

et al. 2006

Synlett

View full text Add to dashboard Cite

The first method for the direct formation of a-oxycarbonates from both aldehydes and ketones is described. N-Methyl-Oalkoxyformate hydroxylamine hydrochloride reagents can be prepared in two high-yielding steps from N-Boc-N-methyl hydroxylamine and were found to be bench stable. These were reacted with a variety of carbonyl compounds to give the corresponding a-functionalised products in 48-98% isolated yield via a proposed [3,3]-sigmatropic rearrangement.

show abstract

Zur Kenntnis unsymmetrischer 3‐Hydroxybiurete 39. Mitt. über Hydroxylamin‐Derivate

Zinner

Stoffel

Hitze

et al. 1969

Archiv der Pharmazie

View full text Add to dashboard Cite

Monosubstituierte 3-Hydroxybiurete erhalt man aus Hydroxyharnstoff und Isocyanaiiureestern, bzw. aus in 3-Stellung substituierten 1-Hydroxyharnstoff-Derivaten und Chlorsulfonylisoc yanat unter nachtraglicher Verseifung des prim. Umsetzungsproduktes. Durch entsprechende Reaktionen liel3en sich in Einzelfallen aus substituierten Hydroxyharnstoffen und Isocyansiiureestern bzw. Acyliocyanaten Derivate des 3-Hydroxybiureta erhalten, die in 1und 5-Stellung verschiedenartige Substituenten tragen, darunter auch hcylgruppen. Unsymmetrical 3-Hydrorybiurets, Part 39Monosubstituted 1-hydroxybiurets are received from hydroxy urea and esters of isocyanic acid, reppectively from in 3-position substituted 1-hydroxy urea derivatives and chlorosulfonyl isocyanate with additional hydrolysis of the primary reaction product. In single cases dcrivatives of 3-hydroxybiureta could be received by reactions of substituted hydroxy urea8 and esters of isocyanic acid, respectively acyl isocyanates. These derivatives carry in 1and 5-position different substituents, also acyl groups.Vor 100 Jahren wurde von Uresler und Stein. als Nebenprodukt einer zu Hydroxyharnstoff fiihrenden Reaktion eine Substanz der Summenformel C,H ,N3032) aufgefunden, deren Struktur nach Erarbeitung einer gut reproduzierbaren Arbeitsvorschrift von Ezner3) als 3-Hydroxybiuret (1) sichergestellt werden konnte. Als Derivate dieses Grundkorpers sind bishcr nur in 1,5-Stellung symmetrisch-disubsti tuierte Verbindungen (3) b e k a n n t g e w~r d e n~-~) .

show abstract

Zur Synthese N‐monosubstituierter O‐Acylhydroxylamine. 38. Mitt. über Hydroxylamin‐Derivate

Cited by 7 publications

References 5 publications

4,5-Dihydropyridazines: x-ray structure of a dimer

4,5-Dihydropyridazines: x-ray structure of a dimer

The Direct Introduction of Carbonates α to Carbonyl Groups

Zur Kenntnis unsymmetrischer 3‐Hydroxybiurete 39. Mitt. über Hydroxylamin‐Derivate

Contact Info

Product

Resources

About