“…As a result, the research produced various novel transformations of nitro compounds, including unprecedented examples of protodenitration. The very first reported protodenitrations utilized readily available reducing agents such as sulfane (Eibner, 1901), [11] tin chloride (Balaban, 1929), [12] and sodium hydrogen sulfite (Taivonen, 1934), [13] producing derivatives 4-6 containing the carbonyl moiety (Figure 1). Later on, between 1938 and 1966, with more sophisticated reductants available, another set of substrates was denitrated using transition-metal catalysed hydrogenation (products 7, 11, and 13, Shriner 1938, Ginzburg 1964, and Bavin 1966), [14,18,20] metallic tin (8, Salukaew, 1951) [15] and sodium (10, Hoffmann, 1964), [17] lithium aluminum hydride (9, Adams, 1952) [16] and electrolysis (12, Masui 1965) [19] (Figure 1).…”