ZnO-beta zeolite mediated simple and efficient method for the one-pot synthesis of quinoxaline derivatives at room temperature

Abstract

Abstract:A rapid and an efficient one-pot method for the synthesis of quinoxalines catalysed by ZnO-beta zeolite at room temperature is described. This environmentally benign method provides several advantages over methods that are currently employed such as asimplework-up,mildreactionconditions,goodtoexcellentyields,andaprocesstorecoverandreusethecatalystforseveralcycles withconsistentactivity. © Versita Sp. z o.o.

Microwave Assisted One‐Pot Multicomponent Synthesis Using ZnO‐β Zeolite Nanoparticle: An Easy Access to 7‐Benzodioxolo[4,5‐b]xanthene‐dione and 4‐Oxo‐tetrahydroindole Scaffolds

“…The Brønsted acid sites of the β‐zeolite have been tuned by altering the metal cations for preparing the modified catalysts with acidity suitable for diverse trans‐esterification reactions . Interestingly, β‐zeolite modified with zinc oxide (ZnO) is an efficient catalyst for a variety of bioactive moieties like 5‐arylidene‐2,4‐thiazolidinedione, quinoxaline derivatives, benzothiazole, tetrahydrobenzo[b]pyrans, and polyhydroquinoline …”

Indion 190 resin: Reusable catalyst for the synthesis of quinoxalines and pyrido-pyrazines at ambient temperature

“…Commonly employed method involves condensation of an aryl-1,2-diamine with a 1,2-dicarbonyl in refluxing ethanol or acetic acid for 2-12 h yielding 34-85% of product [10]. Several improved methods reported in the literature for the synthesis of quinoxalines include microwave synthesis [11], the use of PEG-400 [12], RuCl-(PPh3)3-TEMPO [13], CAN [14], CuSO4.5H2O [15], SA/MeOH [16], montmorillonite K-10 [17], InCl3 [18], Zn/proline [19], Ga(OTf)3 [20], HClO4-SiO2 [21], -cyclodextrins in water [22], FeMAP [23], TiO2-P25 [24], ZnO-beta zeolite [25], silica-supported antimony(III) chloride [26] as catalysts.…”

Polyaniline/SiO2Catalyzed One-pot Mannich Reaction: An Efficient Synthesis of β-amino Carbonyl Compounds

“…In the continuation of our work, to develop new heterogeneous catalysts for the synthesis of heterocyclic and biologically active compounds, [36][37][38] herein, we report a polyaniline/SiO 2 catalyzed three-component Mannich reaction of acetophenone, aromatic aldehydes, and aromatic amines, which led to β-amino ketones under mild reaction conditions.…”