ZIF-8 self-etching method for Au/polydopamine hybrid cubic microcapsules with modulated nanostructures

Abstract

A one-step strategy combining in situ redox-oxidation polymerization and a ZIF-8 sacrifice template is reported for constructing Au/PDA cubic microcapsules.

Synthesis and modification of ZIF-8 and its application in drug delivery and tumor therapy

“…The Au/PDA cube microcapsules were added to an ibuprofen/n-hexane solution at room temperature, and then stirred and centrifuged to obtain the Au/PDA cube drug-loaded microcapsules loaded with the analgesic and anti-inammatory drug ibuprofen. 102 Aer Zou et al synthesized ZIF-8 nanocrystals, they used an improved sol-gel method to coat the surface of ZIF-8 nanocrystals with a mesoporous silica layer to form ZIF-8@MSN. Then the ZIF-8 was naturally degraded in dilute hydrochloric acid solution to obtain monodispersed hollow mesoporous silica (HMSN).…”

Current Advances of Hollow Capsules as Controlled Drug Delivery Systems

“…More importantly, this fabrication method enables the pre‐loading encapsulation of therapeutic agents with different active groups including inorganic groups without any effects of harsh chemicals for silica core removal. Besides that, the ability of using PDA to induce the self‐etching of metal organic framework ZIF‐8, resulting to the formation of hollow cubic cubes was also mentioned in various reports …”

“…Besides that, the ability of using PDA to induce the self-etching of metal organic framework ZIF-8, resulting to the formation of hollow cubic cubes was also mentioned in various reports. [74][75][76]…”

Nano-based theranostic approaches for infection control: current status and perspectives

“…Metal-organic frameworks (MOFs), highly coordinated porous crystals comprising of metal nodes and organic ligands, have garnered much attention due to their customizable features and diverse biomedical applications, including imaging, sensing and drug delivery. [169][170][171] Currently, more than 90 000 MOFs are being synthesized. 172 While their synthetic methods may vary, their antimicrobial activities, as well as monitoring abilities, typically originated from the embedded metals or ligands (e.g., antimicrobials and porphyrins), which may detect microbial cells while facilitating the generation of ROS to inhibit the growth of microbes, including E. coli, S. aureus, MRSA and C. albicans.…”