2006
DOI: 10.1021/nl052134m
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Zeptogram-Scale Nanomechanical Mass Sensing

Abstract: Very high frequency (VHF) nanoelectromechanical systems (NEMS) provide unprecedented sensitivity for inertial mass sensing. We demonstrate in situ measurements in real time with mass noise floor approximately 20 zg. Our best mass resolution corresponds to approximately 7 zg, equivalent to approximately 30 xenon atoms or the mass of an individual 4 kDa molecule. Detailed analysis of the ultimate sensitivity of such devices based on these experimental results indicates that NEMS can ultimately provide inertial m… Show more

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Cited by 969 publications
(713 citation statements)
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“…As shown in figure 4, a large SNR of around 100 dB can be obtained with our device. This value is larger than data reported previously (see [1,10] for example). To measure the noise, we followed the technique described in [18].…”
Section: Noise and The Signal To Noise Ratiocontrasting
confidence: 68%
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“…As shown in figure 4, a large SNR of around 100 dB can be obtained with our device. This value is larger than data reported previously (see [1,10] for example). To measure the noise, we followed the technique described in [18].…”
Section: Noise and The Signal To Noise Ratiocontrasting
confidence: 68%
“…Recently, mass resolution down to 7 zg Hz −1/2 [1] has been demonstrated using a metallic gauge layer deposited on the top of a cantilever. Another approach [14] consists in using a doped silicon nanowire that produces a second-order piezoresistive effect for large displacements of the nanowire.…”
Section: Introductionmentioning
confidence: 99%
“…Their small size, extremely low power consumption, and ultrafast operational speed are among the virtues that have been exploited for significant applications ranging from single-electron spin detection [1] and Zeptogram scale mass sensing [2] to rf communications [3], semiconductor superlattice [4,5], and many others [6][7][8][9][10][11][12][13][14]. From the perspective of basic science, NEM systems represent a novel class of high-dimensional nonlinear dynamical systems.…”
Section: Introductionmentioning
confidence: 99%
“…To see why NEM systems are fundamentally nonlinear and thus chaos can arise, we take as an example an electrostatically driven nanowire [1,2,8,9,[12][13][14][20][21][22], a paradigm for investigating nonlinear behaviors in nanoscale systems [15,18,19]. When the nanowire moves, the amount of stretching can be expressed as an integral of nonlinear functions of the displacements (see Sec.…”
Section: Introductionmentioning
confidence: 99%
“…Due to its low mass density and extraordinary mechanical properties, graphene is an ideal nanomaterial for nanoelectromechanical systems (NEMS), e.g., for extremely small mass sensing. 3,4 In fact, understanding basic properties of graphene plays a critical role in improving the performance of nano-electromechanical devices. Accurate measurements of these parameters are essential to model the performance of NEMS devices.…”
mentioning
confidence: 99%