Y-chromosomal STR variation in Kurds and Arabs population in Iraqi Kurdistan

Fattah, Yousif M.; Mohammed, Ahmed Basheer; Hussien, Nasreen Jalal

doi:10.18203/2320-6012.ijrms20191650

Cited by 3 publications

(4 citation statements)

References 9 publications

(12 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…All these primers that are used during this study can be considered informative due to its high values. The studies' outcomes are in agreement with results that have been done byFattah et al, (2019) they were reported high values of PIC. Furthermore,Naji (2020) found that DYS19 and DYS393 primers were the most polymorphic in comparing to other primers.…”

supporting

confidence: 91%

“…High number of allele per each population suggests a high amounts of genetic diversity in that population. Fattah et al (2019) reported that the average number of alleles in Behdinan population was 5.125, whereas in this study the number of alleles in Behdinan population (7.8) was much higher, this may be due to use larger number of markers. The allele frequency in these three populations were not the same with each other.…”

Section: )contrasting

confidence: 63%

See 1 more Smart Citation

Y- chromosomal STR Variation in Arab, Soran and Behdinan Kurds population in Kurdistan region of Iraq

Ehsaan

Fattah²

2022

biochemmed

View full text Add to dashboard Cite

Background: Over than eight tenant groups make up Kurdistan region of Iraq local populations. Overall majority of the inhabitants are Muslim Kurds, followed by Yezidi Kurds. Alternative groups including Armenians, Assyrian, Chaldea Syriacs as well as a little minority of Arab and Turkmen individuals. Methods: A total of 60 unrelated males from three population groups in Kurdistan region of Iraq Arabs, Soran and Behdinan kurd were successfully analyzed for ten Y- chromosome STRs (DYS19, DYS390, DYS393, DYS437, DYS439, DYS447, DYS460, DYS461, DYS481, DYS576). Whole DNA has been extracted from the blood samples using DNA extraction kit. PCR products were run on 8% polyacrylamide gel with a 50bp DNA ladder marker to size the bands for each sample. silver staining was used to identify the DNA bands. Power Marker V3.25 software was used successfully to determine a variety of genetic parameters which include total allele number, allele frequency, gene diversity and polymorphic information content (PIC). Phylogenetic tree was constructed by MEGA-X software. Results: The total number of alleles identified in the three populations was 155. The size of the alleles ranged from 112bp to 245bp. The DYS19 had the highest diversity (GD: 0.941), whereas DYS393 locus had the lowest value among all (GD: 0.813). The Dendrogram split the populations into two main clusters: Arabs in one cluster, whereas Soran and Behdinan in another cluster. Conclusions: This study validates that the discrimination potential of high-resolution Y-STR typing and supports the main datasets on the samples from Kurdistan region of Iraq. The comparison of two group of Kurds and Arab datasets offers an intriguing total pattern of Kurd groups. Meaning that Sorans are genetically closer to the Behdinan population.

show abstract

supporting

confidence: 91%

Section: )contrasting

confidence: 63%

Y- chromosomal STR Variation in Arab, Soran and Behdinan Kurds population in Kurdistan region of Iraq

Ehsaan

Fattah²

2022

biochemmed

View full text Add to dashboard Cite

show abstract

“…High number of alleles per each population suggests high amount of genetic diversity in the population. Fattah et al (2019) reported that the average number of alleles in Kurd population was 5.125, while in this study the number of alleles in Kurd population (10.91) was much higher, this may be due to the use of larger number and different primers. High number of alleles within each population indicates a great level of genetic diversity.…”

Section: Discussioncontrasting

confidence: 54%

Y-chromosomal Short Tandem Repeat Variation in Kurd, Assyrian, and Armenian populations in Iraq Kurdistan

Khalid

Fattah

2023

Polytechnic j.

View full text Add to dashboard Cite

Background: North central Middle Eastern countries Iran, Iraq, Turkey, and Syria all have persistent Kurdish regions. Over thousands of years, several ethnicities have immigrated, settled, or resided in the region, including Turks, Persians, Arabs, Kurds, Armenians, Assyrians, Chechens, and Azeris. Methods: Eleven Y-chromosome STRs were evaluated in a total of 90 unrelated males from the Kurds, Armenians, and Assyrians populations in the Kurdistan region of Iraq (DYS19, DYS390, DYS393, DYS426, DYS437, DYS439, DYS447, DYS460, DYS461, DYS481, and DYS576). Using a DNA extraction kit, total DNA was isolated from leukocytes. PCR products were run on 8% polyacrylamide gel with a 50bp ladder DNA marker to size the bands, and silver staining was used to identify the DNA bands. Power Marker V3.25 software was used to determine variety of genetic parameters, including total allele number, allele frequency, gene diversity, polymorphic information content (PIC), and phylogenetic tree was constructed by MEGA-X software. Results: The total number of alleles identified in the three populations was 380. The sizes of the alleles ranged from 87bp to 275bp.The most diverse loci were DYS447 and DYS576 (GD: 0.949), whereas DYS426 showed the least diversity (GD:0.896). The Phylogenetic tree divided the populations into two main clusters: The Kurdish and Armenian clades in one cluster and the Assyrian in another cluster. Few of dendrogram leaves from the three examined groups were admixed with each other. Conclusions: This study confirms the high-resolution Y-STR typing's ability to discriminate. We conclude that the genetic distance between Kurd and Armenians is less than the genetic distance between the Kurd and the Assyrians, meaning that the Armenians population are genetically closer to the Kurds population.

show abstract

“…The current study, the first to our knowledge, focuses on one group of the Kurdish population (Sorani Kurds) in Iraq, separated from the Kurmanji Kurdish group in the northwest of Iraq on the border with Turkey. In addition, a higher number of population samples were collected than in the previous paternal lineage studies of the Kurdish population [ 19 , 20 , 47 ], which is also an important consideration in obtaining more reliable results with greater precision and power.…”

Section: Discussionmentioning

confidence: 99%

Population genetic study of 17 Y-STR Loci of the Sorani Kurds in the Province of Sulaymaniyah, Iraq

Albarzinji

Abdulkarim

Hussein³

et al. 2022

BMC Genomics

View full text Add to dashboard Cite

Background The Kurds as an ethnic group are believed to be a combination of earlier Indo-European tribes who migrated and inhabited a mountainous area thousands of years ago. However, as it is difficult to describe the precise history of their origin, it is necessary to investigate their population relationship with other geographical and ethnic groups. Results Seventeen Short Tandem Repeat markers on the Y chromosome (Y-STR) included in the AmpFLSTR™ Yfiler™ PCR Amplification Kit (Thermo Fisher Scientific, USA) were used to type DNA samples from the Sorani (Central) Kurdish population in Sulaymaniyah province. One hundred fifty-seven haplotypes were obtained from 162 unrelated male individuals. The highest and lowest gene diversities were DYS385a/b (GD = 0.848) and DYS392 (GD = 0.392), respectively. The haplotypes were used to predict the most likely haplogroups in the Sulaymaniyah population. Conclusion Haplogroup prediction indicated predominance (28%) of subclade J2 (44/157) in the Sorani Kurds, northeast of Iraq. The pairwise genetic distance results showed that the Kurdish group clustered along with Asian populations, whereas the furthest countries were Europeans and Africans.

show abstract

Y-chromosomal STR variation in Kurds and Arabs population in Iraqi Kurdistan

Cited by 3 publications

References 9 publications

Y- chromosomal STR Variation in Arab, Soran and Behdinan Kurds population in Kurdistan region of Iraq

Y- chromosomal STR Variation in Arab, Soran and Behdinan Kurds population in Kurdistan region of Iraq

Y-chromosomal Short Tandem Repeat Variation in Kurd, Assyrian, and Armenian populations in Iraq Kurdistan

Population genetic study of 17 Y-STR Loci of the Sorani Kurds in the Province of Sulaymaniyah, Iraq

Contact Info

Product

Resources

About