Xanthones from the bark of Garcinia pedunculata

Vo, Hau; Nguyen, Ngoc-Thao T.; Maas, Gerhard; Werz, Udo; Pham, Hung D.; Nguyen, Lien‐Hoa D.

doi:10.1016/j.phytol.2012.08.009

Cited by 11 publications

(8 citation statements)

References 9 publications

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“…In Bangladesh, it is an underutilized fruit found in the north-eastern part of the country. The mature fruit is seldom used in cooking to impart sourness in curries and pulses (Islam et al, 2015), but it has many medicinal properties including antidiabetic, antiscorbutic, antidiarrhoeic, astringent, and cardiotonic (Vo et al, 2012;Sarma et al, 2016;Ali et al, 2017). To date, many studies have explored the pharmacological activity of G. pedunculata, but no attention has been paid to its allelopathic activity.…”

Section: Introductionmentioning

confidence: 99%

Study of the allelopathic activity of Garcinia pedunculata Roxb

Rob

Noguchi

2019

Plant Omics

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The allelopathic properties of plants can be used as an alternative weed control method to reduce the use of synthetic herbicides. Accordingly, the present study was carried out to determine the allelopathic activity of Garcinia pedunculata. Six different concentrations of aqueous methanol extracts of G. pedunculata fruit were prepared and used to determine their effect on the growth of eight test plants: alfalfa (Medicago sativa L.), cress (Lepidum sativum L.), lettuce (Lactuca sativa L.), rapeseed (Brassica napus L.), barnyard grass (Echinochloa crus-galli (L.) P. Beauv.), foxtail fescue (Vulpia myuros (L.) C.C. Gmel.), Italian ryegrass (Lolium multiflorum Lam.), and timothy (Phleum pratense L.). The test plants were grown in Petri dishes and after 48 h incubation, the length of the roots and shoots of the seedlings was measured and compared with control seedlings. Experiments were carried out in a completely randomized design (CRD). Analysis of variance (ANOVA) of the data was performed using the SPSS statistical package, and the I50 values were measured from a regression equation. The extracts at each concentration significantly inhibited the shoot and root growth of all the test plants, except the concentration of 0.001 g dry weight equivalent extract/mL, compared with control. At a concentration of 0.3 g of dry weight equivalent extract/mL, the shoot and root growth of all the tested plants were completely inhibited, except the shoot growth of barnyard grass. The degree of inhibition increased in line with increased extract concentration. The shoots of alfalfa and the roots of barnyard grass were determined to be the most susceptible to the G. pedunculata extract based on the concentration of extract resulting in 50% (I50) growth inhibition of the test plants. These results suggest that G. pedunculata may have allelopathic potential and may possess allelochemicals. From our study, we can conclude that G. pedunculata could be developed as an eco-friendly weed control option.

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Section: Introductionmentioning

confidence: 99%

Study of the allelopathic activity of Garcinia pedunculata Roxb

Rob

Noguchi

2019

Plant Omics

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“…New xanthones and a series of new polyisoprenylated benzophenones, named guttiferones or schomburgkianones, were isolated from the Garcinia species of Vietnam. New xanthones, 1-Omethylglobuxanthone (57) from the bark of G. vilersiana, 48) merguenone (58) from the bark of G. merguensis, 49) mangoxanthone (59) from the heartwood of G. mangostana, 50) 6-O-demethyloliverixanthone (60) and schomburgxanthone (61) were isolated from the bark of G. schomburgkiana, 51) pedunxanthones A-C (62-64) from the bark and pedunxanthones D-F (65-67) from the pericarp of G. pedunculata, 52,53) oblongixanthones F-H (68-70) from the twigs of G. oblongifolia, 54) planchoxanthone (71) from the pericarp of G. planchonii, 55) and xanthochymusxanthones A (72) and B (73) from the bark of G. xanthochymus 56) (Fig. 6).…”

Section: The Genusmentioning

confidence: 99%

“…47) 6-O-Demethyloliverixanthone (60) from G. schomburgkiana showed weak cytotoxic activity against HeLa (human cervical cancer) cell lines (IC 50 16.7±1.9 µg/mL). 51) Pedunxanthone D (65) is an active compound against HeLa and NCI-H460 (human lung cancer) cells, with IC 50 values of 24.9±0.4 and 26.1±1.5 µg/mL, respectively. 53) The new polyisoprenylated benzophenones guttiferones Q-S (74-76) were tested for three human cancer cell lines: MCF-7, HeLa, and NCI-H460.…”

Section: The Genus Ficus (Moraceae Family)mentioning

confidence: 99%

New Compounds and Potential Candidates for Drug Discovery from Medicinal Plants of Vietnam

Giang

Otsuka

2018

CHEMICAL & PHARMACEUTICAL BULLETIN

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The study of natural products introduces interesting new bioorganic structures and potential candidates for the drug discovery stage in the development of innovative drugs. Vietnam enjoys a broad biodiversity of native plant species, microorganisms, marine organisms, and a long tradition of using herbal remedies. Thus, the study of medicinal plants in determining the basis of their efficacy and safety is an important task for modern researchers in Vietnam. The present review covers literature on new compounds elucidated from the systematic study of medicinal plants within some popular genera in Vietnam, as well as their significant biological activities.

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“…%  SD Plachoxanthone (1) 19.5  0.07 Garcinianone A (2) 21.9  0.3 Cowanin 315.7  0.2 Rubraxanthone 415.9  0.1 β-Mangostin (5) 14.4  0.2 Dulcisxanthone B (6) 16.0  0.2 Guttiferone Q 72.7  0. 13…”

Section: Compoundsmentioning

confidence: 99%

“…Column chromatography of an n-hexane extract of the pericarp of G. planchonii led to the isolation of planchoxanthone (1), garcinianone A (2) [7], cowanin (3) [8,9], rubraxanthone (4) [10], β-mangostin (5) [11], dulcisxanthone B (6) [12], and guttiferone Q (7) [6].…”

mentioning

confidence: 99%

Isoprenylated Xanthone and Benzophenone Constituents of the Pericarp of Garcinia planchonii

Trinh

Tran

et al. 2014

Natural Product Communications

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A new xanthone, planchoxanthone (1), together with six known compounds, garcinianone A (2), cowanin (3), rubraxanthone (4), β-mangostin (5), dulcisxanthone B (6), and guttiferone Q (7), were isolated from an n-hexane extract of the pericap of Garcinia planchonii. Their structures were elucidated using spectroscopic methods. Antioxidant activity of the isolated compounds was tested using the DPPH free radical scavenging assay.

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Xanthones from the bark of Garcinia pedunculata

Cited by 11 publications

References 9 publications

Study of the allelopathic activity of Garcinia pedunculata Roxb

Study of the allelopathic activity of Garcinia pedunculata Roxb

New Compounds and Potential Candidates for Drug Discovery from Medicinal Plants of Vietnam

Isoprenylated Xanthone and Benzophenone Constituents of the Pericarp of Garcinia planchonii

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