Introduction: Leprosy is a disease that carried the characteristic of incurable and disfiguring for years, causing the social segregation of patients before the family and society.Objective: To describe the repercussion of segregation in the lives of children separated by leprosy who lived in Oswaldo Cruz School.Method: This is a qualitative study with the methodological referential Oral History of Life. The sample consisted of 52 family members of former patients segregated in the São Francisco of Assis Cologne Hospital, registered in the Reintegration Movement of People Affected by Leprosy in RN (MORHAN Potiguar). The network was structured from the zero point and consists of ten collaborators. Data were collected through individual interviews, which were recorded, transcribed and submitted to thematic content analysis.Results: Emerged four themes: broken ties (broach the consequences in family relationships established by the experience of having a relative affected by leprosy); stigmatized (emphasize the obstacles in social relationships experienced by family member of leprosy former patients, who although healthy, were victims of social exclusion, stigma and prejudice); primary school (reveals the bad treatment experienced in Oswaldo Cruz School, as well as the resilience process of education received); from leprosy to Hansen's disease (were presented reflections made by collaborators related to leprosy control policy in the past and present).