Wide-range tracking and LET-spectra of energetic light and heavy charged particles

Granja, Carlos; Oancea, Cristina; Jakůbek, J.; Marek, Lukáš; Benton, E. R.; Kodaira, Satoshi; Ruciński, Antoni; Gajewski, J.; Stasica, Paulina; Zach, V.; Štursa, Jan; Chvátil, David; Krist, Pavel

doi:10.1016/j.nima.2020.164901

Cited by 28 publications

(31 citation statements)

References 69 publications

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“…The GATE framework offers access to information on single particle interactions, thus, enabling calculation of single particle LET in a voxelized patient geometry. Figure 7 shows dose and LET d distributions, as well as LET spectra for 150 MeV therapeutic proton pencil beam at the Bragg peak depth computed with GATE and measured experimentally with a TimePix detector [49]. In addition, the estimation of the biological dose will be proposed through the BioDoseActor [5].…”

Section: Dose-related Applicationsmentioning

confidence: 99%

The OpenGATE ecosystem for Monte Carlo simulation in medical physics

et al. 2022

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This paper reviews the technical ecosystem of Gate, an open-source Monte Carlo simulator for medical physics. Based on the shoulders of Geant4, the principal modules (geometry, physics, scorers) are described together with brief descriptions of some key concepts (Volume, Actors, Digitizer). The main source code repositories are described together with the automated compilation and tests processes (Continuous Integration). We then described how the OpenGATE collaboration managed the collaborative development of about one hundred developers during almost 20 years. The impact of Gate on medical physics and cancer research is then summarized. Finally, future development perspectives are indicated.

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Section: Dose-related Applicationsmentioning

confidence: 99%

The OpenGATE ecosystem for Monte Carlo simulation in medical physics

et al. 2022

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“…The detection and analysis of particles as single isolated tracks provide extensive and complete spectral and tracking information [8,9]. Results and data products can be derived at the detailed event-by-event level according to the radiation field detection degrees of freedom [5,6] such as (i) particle-event type, (ii) deposited energy (energy loss), (iii) direction (pitch angle to the sensor plane), (iv) deposited dose, (v) linear energy transfer (LET).…”

Section: Low-intensity Fields: Spectral-tracking Imaging Detection Of...mentioning

confidence: 99%

MiniPIX Timepix3 — a miniaturized radiation camera with onboard data processing for online characterization of wide-intensity mixed-radiation fields

Granja¹,

Jakůbek²,

Soukup³

et al. 2022

J. Inst.

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The miniaturized radiation camera MiniPIX TPX3 is designed for detailed and wide-range measurements of mixed-radiation fields present in many applications such as radiotherapy and space radiation in outer orbit. The highly integrated instrumentation utilizes a single connector for control and readout for flexible measurements and quick deployment. The device features an option to process the registered data on the same device with limited resolution and basic particle-type resolving power. A novel readout and data processing technique exploits the detector high granularity and double per-pixel signal electronics to measure and characterize radiation fields of high intensity over a wide range with basic particle-type discrimination.

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“…The threshold calibration and the pixelby-pixel calibration was performed by the company ADVACAM using X-ray radiation sources of different energies [23]. When a particle reaches the detector's sensor, the charge diffuses in both horizontal and lateral directions and spreads over several pixels, creating the so-called "cluster", which is identified as a single particle track [24]. In figures 2(a) and (b), there are two illustrations of 2D and 3D per-pixel deposited energy by clusters produced by scattered particles that hit the detector's sensor surface (in this case 100 μm thick Si sensor).…”

Section: Detector Operation and Readout Modesmentioning

confidence: 99%

Stray radiation produced in FLASH electron beams characterized by the MiniPIX Timepix3 Flex detector

Oancea¹,

Bălan²,

Pivec³

et al. 2022

J. Inst.

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This work aims to characterize ultra-high dose rate pulses (UHDpulse) electron beams using the hybrid semiconductor pixel detector. The Timepix3 (TPX3) ASIC chip was used to measure the composition, spatial, time, and spectral characteristics of the secondary radiation fields from pulsed 15–23 MeV electron beams. The challenge is to develop a single compact detector that could extract spectrometric and dosimetric information on such high flux short-pulsed fields. For secondary beam measurements, PMMA plates of 1 and 8 cm thickness were placed in front of the electron beam, with a pulse duration of 3.5 µs. Timepix3 detectors with silicon sensors of 100 and 500 µm thickness were placed on a shifting stage allowing for data acquisition at various lateral positions to the beam axis. The use of the detector in FLEXI configuration enables suitable measurements in-situ and minimal self-shielding. Preliminary results highlight both the technique and the detector’s ability to measure individual UHDpulses of electron beams delivered in short pulses. In addition, the use of the two signal chains per-pixel enables the estimation of particle flux and the scattered dose rates (DRs) at various distances from the beam core, in mixed radiation fields.

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Wide-range tracking and LET-spectra of energetic light and heavy charged particles

Cited by 28 publications

References 69 publications

The OpenGATE ecosystem for Monte Carlo simulation in medical physics

The OpenGATE ecosystem for Monte Carlo simulation in medical physics

MiniPIX Timepix3 — a miniaturized radiation camera with onboard data processing for online characterization of wide-intensity mixed-radiation fields

Stray radiation produced in FLASH electron beams characterized by the MiniPIX Timepix3 Flex detector

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