Wide Dynamic Range CMOS Potentiostat for Amperometric Chemical Sensor

Abstract

Presented is a single-ended potentiostat topology with a new interface connection between sensor electrodes and potentiostat circuit to avoid deviation of cell voltage and linearly convert the cell current into voltage signal. Additionally, due to the increased harmonic distortion quantity when detecting low-level sensor current, the performance of potentiostat linearity which causes the detectable current and dynamic range to be limited is relatively decreased. Thus, to alleviate these irregularities, a fully-differential potentiostat is designed with a wide output voltage swing compared to single-ended potentiostat. Two proposed potentiostats were implemented using TSMC 0.18-μm CMOS process for biomedical application. Measurement results show that the fully differential potentiostat performs relatively better in terms of linearity when measuring current from 500 pA to 10 uA. Besides, the dynamic range value can reach a value of 86 dB.

Wearable and Miniaturized Sensor Technologies for Personalized and Preventive Medicine

“…Many non‐invasive sensors to measure the concentration of biomarkers in readily available body fluids such as sweat, tears, and saliva are based on miniaturized, planar electrochemical cell technology. Figure a,b shows a simplified schematic of the working mechanism of these amperometric sensors . They usually consist of working (WE), counter (CE), and reference (RE) electrodes .…”

Desarrollo y Evaluación de un Potenciostato Electrónico Digital de Bajo Costo para la Cuantificación de Sustancias Químicas Mediante Biosensores Amperométricos

“…En la instrumentación moderna el potenciostato, así como los amplificadores y otros módulos empleados para acondicionar las señales de corriente y potencial, son dispositivos electrónicos analógicos construidos con amplificadores operacionales (Wang, 2010) (Bard, 2000).…”

Development of a low cost potentiostat using ATXMEGA32

“…Recently, there has been an increasing interest in developing potentiostat application such as for metal corrosion analysis, environmental monitoring, quality control of food and medicines, biosensor, chemical sensor [1][2][3][4][5][6], and protein sensor for the waste dialysate material [7]. Gopinath and Russell (2006) have been successfully developing a low cost portable programmable potentiostat which using 10 bits ADC (analog to digital converter) [8].…”