Whole genome sequence of a New Delhi metallo-β-lactamase 1-producing Proteus mirabilis isolate SNYG35 from broiler chicken in China

Xie, Xin; Zhang, Julin; Wang, Hongning; Lei, Changwei

doi:10.1016/j.jgar.2020.12.023

Cited by 9 publications

(5 citation statements)

References 6 publications

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“…Among the positive bacteria carrying bla NDM-1 gene reported in China from 2012 to 2016, southwest China reported the most ( Jia et al, 2018 ). In 2021, the first report of NDM-1 producing P. mirabilis in broiler chickens was in Chengdu, Sichuan, China ( Xie et al, 2021 ). In this study, we isolated the NDM-1 resistance gene for the first time in Shandong, China.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and characteristics of multidrug-resistant Proteus mirabilis from broiler farms in Shandong Province, China

Peng

Zhang

et al. 2022

Poultry Science

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Section: Discussionmentioning

confidence: 99%

Prevalence and characteristics of multidrug-resistant Proteus mirabilis from broiler farms in Shandong Province, China

Peng

Zhang

et al. 2022

Poultry Science

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“…Carbapenem-resistant strains, including Acinetobacter lwoffii carrying the bla NDM-1 gene, were identified in chicken farms, duck farms, and a pig abattoir in China in 2010. The presence of P. mirabilis , a bacterium capable of harboring NDM, was documented in broiler chickens in 2021 ( Xie et al ., 2021 ). A recent study conducted in China documented the prevalence of carbapenem-resistant E. coli , P. mirabilis , and K. pneumoniae in broiler fattening farms ( Su et al ., 2023 ).…”

Section: Discussionmentioning

confidence: 99%

Phenotypic and genotypic characterization of extended spectrum beta-lactamase producing E. coli harboring carbapenem and colistin resistant genes from poultry farms in Egypt

Ali,

Abdelaziz,

Kamel

et al. 2024

Open Vet J

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Background: Extended spectrum beta-lactamase (ESBL) producing E. coli is implicated in high rate of human infections globally. Uprising of carbapenem and colistin resistance further hinders the treatment potentials of these infections. This study was conducted to assess the phenotypic and genotypic characterization of carbapenem and colistin resistance between ESBL producing E. coli isolates obtained from chicken respiratory tract in El-Sharkia government, Egypt. Methods: Lung samples, 250, from 50 chicken farms were processed for isolation, identification and serotyping of E. coli. Antimicrobial resistance was detected by disk diffusion. ESBL phenotypic occurrence was also examined by double disc synergy. PCR/sequencing were used to investigate ESBL (β-lactamase (bla)- TEM, bla SHV, and bla CTX-M ), colistin (mcr-1), and carbapenem (bla NDM, bla VIM and bla KPC) resistant genes. Results: The results displayed that 140/250 (56%) were detected to be E. coli. All E. coli isolates had an elevated multi-antimicrobial resistance (MAR) index value (>0.2) and 65.7 % were proven to produce ESBL. Among 92 ESBL phenotypes 55 (59.7%), 32 (34.7%), 18 (19.6%), and 37 (40.2%) isolates harbor bla TEM-3, bla SHV-4, bla CTX-M-1, bla CTX-M-14 respectively. The bla NDM-1 gene was detected in all 40/50 carbapenem resistant phenotypes that represents 28.5% of all E. coli and 43.4% of ESBL isolates. The bla VIM and bla KPC were not found in any E. coli isolate. In addition, mobilized colistin resistance (mcr)-1 gene exhibited high prevalence; 64 (69.5%) among ESBL isolates. Conclusion: The reported high frequency of ESBL-producers especially carbapenem and colistin-resistant E. coli would account for a public health threat in the society.

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“…One of these isolates, Acinetobacter lwoffii, was identified as positive for bla NDM−1 , particularly on a 270 kb plasmid (65). In 2021, NDM-producing P. mirabilis was reported in broiler chickens (68). The isolate harbors a plasmid named pSNYG35, a pPrY2001-like plasmid that shares high nucleotide identity with pHFK418-NDM and an NDM-1-encoding plasmid from clinical P. mirabilis.…”

Section: Carbapenem Resistance In Poultrymentioning

confidence: 99%

An overview of carbapenem-resistant organisms from food-producing animals, seafood, aquaculture, companion animals, and wildlife

2023

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Carbapenem resistance (CR) is a major global health concern. CR is a growing challenge in clinical settings due to its rapid dissemination and low treatment options. The characterization of its molecular mechanisms and epidemiology are highly studied. Nevertheless, little is known about the spread of CR in food-producing animals, seafood, aquaculture, wildlife, their environment, or the health risks associated with CR in humans. In this review, we discuss the detection of carbapenem-resistant organisms and their mechanisms of action in pigs, cattle, poultry, seafood products, companion animals, and wildlife. We also pointed out the One Health approach as a strategy to attempt the emergency and dispersion of carbapenem-resistance in this sector and to determine the role of carbapenem-producing bacteria in animals among human public health risk. A higher occurrence of carbapenem enzymes in poultry and swine has been previously reported. Studies related to poultry have highlighted P. mirabilis, E. coli, and K. pneumoniae as NDM-5- and NDM-1-producing bacteria, which lead to carbapenem resistance. OXA-181, IMP-27, and VIM-1 have also been detected in pigs. Carbapenem resistance is rare in cattle. However, OXA- and NDM-producing bacteria, mainly E. coli and A. baumannii, are cattle's leading causes of carbapenem resistance. A high prevalence of carbapenem enzymes has been reported in wildlife and companion animals, suggesting their role in the cross-species transmission of carbapenem-resistant genes. Antibiotic-resistant organisms in aquatic environments should be considered because they may act as reservoirs for carbapenem-resistant genes. It is urgent to implement the One Health approach worldwide to make an effort to contain the dissemination of carbapenem resistance.

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Whole genome sequence of a New Delhi metallo-β-lactamase 1-producing Proteus mirabilis isolate SNYG35 from broiler chicken in China

Cited by 9 publications

References 6 publications

Prevalence and characteristics of multidrug-resistant Proteus mirabilis from broiler farms in Shandong Province, China

Prevalence and characteristics of multidrug-resistant Proteus mirabilis from broiler farms in Shandong Province, China

Phenotypic and genotypic characterization of extended spectrum beta-lactamase producing E. coli harboring carbapenem and colistin resistant genes from poultry farms in Egypt

An overview of carbapenem-resistant organisms from food-producing animals, seafood, aquaculture, companion animals, and wildlife

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