What is your diagnosis? Cutaneous mass in the mammary region of a dog

Grandi, Fabrizio; Monteiro, Leonardo de Almeida; Fernandes, Thais Rosalen; Salgado, Breno S.; Rocha, Noeme Sousa

doi:10.1111/j.1939-165x.2011.00290.x

Cited by 4 publications

(7 citation statements)

References 3 publications

(4 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, it is known that SCC has greater potential for invasiveness than for metastasis, and in cases where metastasis occurs, the most common sites are the regional lymph nodes (16). Two of the cases of ASCC reported in the veterinary literature to date have not reported evidence of metastasis (4,8), while one case had features consistent with lymph node metastasis (20). In the current report, we observed invasive behavior as well as metastasis of the neoplasia to the regional submandibular lymph nodes, with an increase in size and an alteration of the normal cellular architecture.…”

Section: Discussionmentioning

confidence: 99%

“…In humans, this variant is rare, but it has been reported in the oral cavity (9,13), nasal cavity (1, 9), vulva (6), palate (9), maxilla (19), cecum (10) and breast (11). ASCC is also rare in animals, with only a few reports that have described ASCC in the mammary region (8) and oral cavity of dogs (4). Thus, the purpose of this report is to describe the gross and microscopic characteristics of submandibular acantholytic squamous cell carcinoma with metastases in a female dog.…”

Section: Introductionmentioning

confidence: 95%

See 1 more Smart Citation

Metastatic submandibular acantholytic squamous cell carcinoma in a dog

Silva¹,

Sarandy²,

Tamiasso³

et al. 2018

BJVP

View full text Add to dashboard Cite

Silva, et al.; Metastatic submandibular acantholytic squamous cell carcinoma in a dog. Braz J Vet Pathol, 2018, 11(1), 19 -23 DOI: 10.24070/bjvp.1983 Abstract A seven-year-old female mixed-breed dog was diagnosed with an uncommon histological variant of squamous cell carcinoma (SCC) with lymph node metastases. Therefore, the objective of this report was to describe the gross and microscopic findings of this uncommon SCC histological variant. Fine-needle aspiration cytology of the mass revealed a squamous cell carcinoma. On necropsy, the submandibular region revealed nodular, multifocal to coalescing, ulcerated masses with firm and fluctuant areas. Furthermore, enlarged submandibular and cervical lymph nodes with loss of normal architecture suggestive of metastasis were present. A definitive diagnosis of submandibular acantholytic squamous cell carcinoma was made upon histopathological evaluation. This variant is rare in humans and animals.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 95%

Metastatic submandibular acantholytic squamous cell carcinoma in a dog

Silva¹,

Sarandy²,

Tamiasso³

et al. 2018

BJVP

View full text Add to dashboard Cite

show abstract

“…In the veterinary literature, there are only a few reported cases of acantholytic SCC in animals. It has not been previously reported in poultry unlike scattered reports of acantholytic SCC in dogs (4,8,21,23) and cattle (12).…”

mentioning

confidence: 78%

Pathologic findings of acantholytic squamous cell carcinoma coexisting with cutaneous cryptococcosis in a Houbara bustard (Chlamydotis undulata)

Kheirandish

Alidadi

Azizi

et al. 2022

Ankara Üniversitesi Veteriner Fakültesi Dergisi

View full text Add to dashboard Cite

A 2-year-old Asian Houbara bustard was presented with a solitary well-defined, firm cutaneous mass on the hock region. Grossly, the mass protruded from the surface was located on the hairless and unpigmented areas of the right hock joint with ulceration and dried hemorrhagic foci. On microscopic examination, ulceration, hemorrhage, as well as hyperkeratosis were observed. Large round, oval to polygonal neoplastic cells extended into the dermis were arranged to form cords, trabeculae, islands or glandular-like structures without keratin pearls. These pseudoglandular structures were composed of pseudolumina containing acantholytic and detached tumor cells. Necrosis of the neoplastic cells was accompanied by infiltration of inflammatory cells particularly heterophils. Unlike pleomorphic tumor cells, mitotic count was almost frequent. No evidence of other abnormalities and tumor metastasis was found. These gross and microscopic features appeared to be suggestive of a rare histologic variant of squamous cell carcinoma (SCC), acantholytic SCC.

show abstract

“…The latter method may induce RBC lysis and remove cellular debris, which may be advantageous for interpretation of some specimens. A unique feature of the Papanicolaou stain is the affinity of Orange G for keratin, which highlights squamous differentiation in cells …”

mentioning

confidence: 99%

“…A unique feature of the Papanicolaou stain is the affinity of Orange G for keratin, which highlights squamous differentiation in cells. 4 Despite the unique advantages of each stain, and virtually complementary staining properties, Romanowsky-type stains are widely favored over tri-chrome stains in veterinary cytopathology. This is probably due to the simplicity of handling air-dried specimens obtained in veterinary practices distant to diagnostic laboratories and greater familiarity of veterinary cytopathologists with Romanowsky-type stains.…”

mentioning

confidence: 99%