What Does the c-Wave Tell Us in Retinal Diseases?

Röver, J.; Mack, Meike; Oschwald, G.

doi:10.1007/978-94-009-7275-9_23

Cited by 4 publications

(5 citation statements)

References 5 publications

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“…Furthermore we showed that in Best's disease and in Stargardt's disease the c-wave is significantly reduced, (Rg'ver, Mack and Schaubele, 1983). Furthermore we showed that in Best's disease and in Stargardt's disease the c-wave is significantly reduced, (Rg'ver, Mack and Schaubele, 1983).…”

Section: Methodsmentioning

confidence: 73%

“…As the component originating in the receptor layer is opposite in polarity from the component of the pigment epithelium, a reduction of the c-wave may be caused either by an increase of the receptorlinked component or by a decrease of the component related to the pigment epithelium. Weingeist, Kobrin and Watzke, 1982; bird shot retinopathy, R6ver, Mack and Schaubele, 1983) in which we know that the deficiency is located in the pigment epithelium support this view. The pigment epithelium, however, reacts most sensitively to all disturbances in all layers of the retina.…”

Section: Discussionmentioning

confidence: 90%

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The C-wave in hereditary degenerations of the ocular fundus

Röver¹,

Bach²

1985

Doc Ophthalmol

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The c-wave of the human direct current ERG may give new insights about the involvement of the retinal pigment epithelium in hereditary degenerations. In our single-sweep recordings from 236 alert patients we saw reduced c-waves not only in vitelliforme macular degenerations but also in dominantly inherited drusen, Stargardt's disease, cone dystrophies, and x-linked retinoschisis. In achromatopsia the c-wave was close to normal. The relationship of the b- and c-wave, however, was altered only in Best's disease, cone dystrophy, and x-linked retinoschisis. We postulate that the c-wave when more severely reduced than the b-wave reflects not merely the dysfunction of the pigment epithelium but more precisely whether this retinal layer is involved earlier than the photoreceptors.

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Section: Methodsmentioning

confidence: 73%

Section: Discussionmentioning

confidence: 90%

The C-wave in hereditary degenerations of the ocular fundus

Röver¹,

Bach²

1985

Doc Ophthalmol

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“…Many properties of the human c-wave and its relation to the electrooculogram (EOG) in diseases of the pigment epithelium were examined (Skoog and Nilsson 1974;R6ver 1982;R6ver et al, 1980, 1982, 1983, Nilsson and Skoog 1980. The question remains, however, whether this test contributes to diagnosis, advising, or therapy of patients.…”

Section: Introductionmentioning

confidence: 99%

C-wave versus electrooculogram in diseases of the retinal pigment epithelium

Röver¹,

Bach²

1987

Doc Ophthalmol

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The c-wave and the electrooculogram (EOG) are retinal potentials predominantly generated by the pigment epithelium. In most diseases both parameters show a parallel decrease in amplitude. However, in patients with dominant drusen, and cone dystrophies, and in clinically nonaffected members of families suffering from vitelliform macula degeneration, the EOG is close to normal whereas the c-wave shows a reduced amplitude. These findings suggest a higher sensitivity of the generators of the c-wave compared with those responsible for the EOG. Thus the direct current electroretinogram provides additional diagnostic information.

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“…In this way, the work of many authors was considerable [3-6, 8, 14, 15], In the last 6 years the clinical evaluation of C waves in various fundus diseases showed that the C wave reflects the function of the retinal pigment epithelium about equally. maybe sometimes with a higher sensitivity than the electrooculogram [9][10][11].…”

Section: Introductionmentioning

confidence: 99%

C Wave Study in Optic Neuritis due to Demyelinating Disease

Moschos

Brοuzas²,

Panagakis³

1990

Ophthalmologica

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The C wave was recorded from 20 eyes suffering from neuritis due to demyelinating disease and in 5 eyes showing optic atrophy due to trauma or to increased intracranial pressure. Our results show that in cases with optic neuritis the C wave amplitude was clearly lower than normal. It is interesting that in the other ‘healthy’, at least clinically, eye the C wave was subnormal too. On the contrary, in the eyes with optic atrophy the C wave was normal. These findings are against the possibility of an efferent neuronal pathway involvement, which influences the level of the retinal pigment epithelium, and support the view of its involvement during the course of the demyelinating disease that causes the optic neuritis.

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What Does the c-Wave Tell Us in Retinal Diseases?

Cited by 4 publications

References 5 publications

The C-wave in hereditary degenerations of the ocular fundus

The C-wave in hereditary degenerations of the ocular fundus

C-wave versus electrooculogram in diseases of the retinal pigment epithelium

C Wave Study in Optic Neuritis due to Demyelinating Disease

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