Well‐defined poly(oxazoline)‐b‐poly(acrylate) amphiphilic copolymers: From synthesis by polymer–polymer coupling to self‐organization in water

Abstract

In this contribution, we report on the self assembly in water of original amphiphilic poly(2-methyl-2-oxazoline)-b-poly(tert-butyl acrylate) copolymers, synthesized by copper catalyzed azide-alkyne cycloaddition (CuAAC) reaction. For such purpose, polyoxazoline (poly(2-methyl-2-oxazoline)) and polyacrylate (poly(tert-butyl acrylate)) are first prepared by cationic ring-opening polymerization (CROP) and atom transfer radical polymerization (ATRP), respectively. Well-defined polymeric building blocks, ω-N 3 -P(t-BA) and -alkyne-P(MOx), bearing reactive chain end groups, are accurately characterized by MALDI-Tof spectroscopy. Then, P(MOx) n -b-P(t-BA) m are achieved by polymer-polymer coupling and are fully characterized by DOSY NMR and size exclusion chromatography, demonstrating the obtaining of pure amphiphilic copolymers. Consequently, the latter lead to the formation in water of well-defined monodisperse spherical micelles (R H = 40-60 nm) which are studied by fluorescence spectroscopy, SLS, AFM and TEM.

Stable antifouling coatings by hydrogen-bonding interaction between poly(2-methyl-2-oxazoline)-block-poly(4-vinyl pyridine) and poly(acrylic acid)

“…The difficulty to synthesize long-chain molecules by the polymer-polymer coupling approach lies in the weak compatibility between P4VP and PMOXA [29]. Consequently, P4VP with shorter chain length was used in preparing PMOXA-b-P4VP diblock copolymer.…”

Polyoxazoline associated with cardanol for bio‐based linear alkyl benzene surfactants

“…who designed copolymers containing both hydrophilic and lipophilic POx blocks . More recently, POx blocks have been linked to bio‐based blocks such as glycopolymers and fatty derivatives or to petro‐based blocks including polysiloxanes, aliphatic polyesters and fluorinated chains, giving various amphiphilic copolymers with surfactant or self‐assembling properties . Their use as a surfactant for instance for emulsion polymerization or solubilization of dyes has recently been reported …”

Amphiphilic photo-induced triblock polyoxazoline through coumarin dimerization: Efficient synthetic tool for nanoparticles

“…Many macromolecular architectures have already been described using hydrophilic and/or hydrophobic 2-oxazoline monomers or coupled to other polymer blocks [45]. The POx could be also combined to other polymerization processes [46]. All these strategies explained the keen interest of the manifold investigations on the decoration of POx using functional terminating agents [47] or initiators [48][49][50][51][52][53][54][55][56][57][58].…”