Vulvo-vaginal ano-gingival syndrome: Another variant of mucosal lichen planus

Abstract

Vulvo-vagino-gingival syndrome was described as a distinctive pattern of erosive plurimucosal lichen planus (LP), and it is a clinical triad of vulval, vaginal, and gingival LP. It can lead to sequelae such as vaginal and urethral stenosis which can have severe implications on the quality of life. We report a case of a 40-year-old female who developed urethral, vaginal, as well as anal stenosis as a result of long-term exclusive mucosal LP involving vulvo-vaginal and anal mucosa along with oral LP without any other cutaneous involvement. This case is being reported because of the rare association of anal LP with vulvo-vagino-gingival syndrome and its gross similarity to lichen sclerosus.

Hypertrophic lichen planus of the vulva – A missed diagnosis

“…It may result in an alteration of the normal architecture including the development of vaginal adhesions, stenosis, and in severe cases, complete obliteration of the vaginal canal and urinary retention. Hewitt–-Pelisse syndrome (vulvo-vaginal- gingival syndrome[ 6 ]) is a form of erosive LP; that involves the vulva, vagina, and mouth. Papulosquamous or classic type presents as small violaceous pruritic papules or plaques with overlying reticulations and involves keratinized and perianal skin.…”

Multi-modal approach in management of vulvo-vaginal gingival syndrome − a rare variant of oral lichen planus

“…Based on the clinical presentation of the lesions, Oral LP is classified into six clinical subtypes. The presence of erosive LP of the vulva and vagina with desquamative gingivitis (DG) has been described as VVGS or Hewitt-Pelisse Syndrome and there are only a few case reports regarding this rare syndrome in the literature [2]. In 1937, Guogerot and Burnier described the coexistence of oral, cervical, and stomach LP lesions with no cutaneous involvement as "plurimucosal LP".…”

“…In 1937, Guogerot and Burnier described the coexistence of oral, cervical, and stomach LP lesions with no cutaneous involvement as "plurimucosal LP". In 1982, Pelisse and colleagues reintroduced a similar variant of mucosal LP as VVGS with erosive lesions involving the oral and vulvovaginal mucosa [1,2]. It is considered as a clinical triad of vulval, vaginal, and gingival lichen planus (LP) and can have significant negative impact on QoL ultimately leading to complications like urethral and vaginal stenosis [3].…”

A novel approach to the treatment of vulvovaginal gingival syndrome

“…Вульвовагинально-гингивальный синдром (ВГС), или синдром Хеватта-Пелиссе, описан в 1982 г. M. Pelisse [4,5] как эрозивная разновидность КПЛ; поражает около 1% женщин. Этот хронический мультисистемный синдром, имеющий клиническое сходство с буллезным пемфигоидом слизистых оболочек и выраженную тенденцию к образованию рубцов и синехий, формированию стеноза пищево-да и влагалища.…”