Volatile fraction of neem oil as a spermicide

Riar, S. S.; Devakumar, C.; Ilavazhagan, G.; Bardhan, J; Kain, A. K.; Thomas, Philip; Singh, Ravi; Singh, B.

doi:10.1016/0010-7824(90)90054-y

Cited by 53 publications

(25 citation statements)

References 3 publications

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“…The plant extracts exhibit some antimicrobial, anti-inflammatory and antipyretic properties (Okpanyi and Ezeukwu, 1981). Also, the anti-fertility effects of the neem oil due to the potential spermicidal effect have been recorded (Lai et al, 1986;Riar et al, 1990). Neem oil also exhibited a spermicidal agent and inhibited sperm motility which highlighted its immuno-contraceptive properties (Upadhay et al, 1990(Upadhay et al, , 1992.…”

Section: Introductionmentioning

confidence: 99%

Investigations of antioxidant and antibacterial activity of leaf extracts of Azadirachta indica

Pokhrel¹,

Rijal²,

Raut³

et al. 2015

Afr. J. Biotechnol.

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Active ingredients of medicinal plants have been used to cure several human diseases. Azadirachta indica is one of the most versatile medicinal plants having a wide spectrum of biological activity due to the presence of large number of bioactive compounds. The present study was conducted to evaluate antimicrobial and antioxidant efficiency and phytochemical screening of A. indica leaf extract using methanol as a solvent. A qualitative phytochemical screening was performed for the detection of various phytochemicals. Then, the quantitative determination of total phenols, flavonoids and proanthocyanidins was done and expressed in terms of gallic acid and rutin equivalent. Total phenolic, flavonoid and proanthocyanidin content were found to be 85.9±4.0, 104.9±5.5 and 65.4±13.9 mg/g of plant extract, respectively. Also, the antibacterial activity was performed using six different bacterial strains: Escherichia coli (ATCC 25922), Staphylococcus aureus (ATCC 25923), Salmonella typhi (ATCC 14028), Klebsiella pneumoniae (ATCC 700603), Pseudomonas aeruginosa (ATCC 27853) and Proteus vulgaris (ATCC 35659). It was found that the maximum zone of inhibition of 22±3 mm was shown against S. aureus using 700 µg plant extract. Similarly, the antioxidant activity of the methanolic extract of plant was also determined and it was found that maximum inhibition obtained was 71.23% when 500 µg plants extract was used.

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Section: Introductionmentioning

confidence: 99%

Investigations of antioxidant and antibacterial activity of leaf extracts of Azadirachta indica

Pokhrel¹,

Rijal²,

Raut³

et al. 2015

Afr. J. Biotechnol.

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“…In other investigations, the active constituents of the oil were identified to be a mixture of six compounds comprising saturated, mono and di-unsaturated free fatty acids and their methyl esters [35] . The oil (0.25-25.00 mg/ mL) had spermicidal effects on human and rat sperm in vitro [36,37] .…”

Section: Antifertility Effectmentioning

confidence: 99%

“…T he oil had embryotoxic effects after vaginal administration to pregnant rats at a dose of 0.25 mL/ animal [37,38] . Embryotoxic effects were also reported following intragastric administration of 4 mL/kg body weight of the oil to pregnant rats on days 6-8 of pregnancy [27] .…”

Section: Teratogenic Effectmentioning

confidence: 99%

Review on pharmacological and toxicologyical effects of oleum azadirachti oil

Koriem

2013

Asian Pacific Journal of Tropical Biomedicine

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“…A high content of saturated fatty acids (16-36% palmitic acid 16:0, 6-24% stearic acid, 25-58% oleic acid, and 6-17% linoleic acid [18,19]) is typical for this oil. Neem oil and especially its volatile fraction, gained by steam distillation, are known for their spermicidal activity [20].…”

Section: Introductionmentioning

confidence: 99%

Volatile compounds and triacylglycerol composition of original Indian fatty plant oils

Krist

Stuebiger

Bail

et al. 2008

Euro J Lipid Sci & Tech

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Some typical original Indian edible and non-edible fatty plant oils were subject of our investigations. Fundamental research was done on analyzing volatile compounds using HS-SPME-GC-MS. In addition, a sensorial evaluation was applied to receive data on the smell of the samples. Furthermore, the typical and prevailing triacylglycerols (TAG) were investigated by MALDI-TOF-MS. Mass spectra reflect the TAG profiles of the whole oil samples based on the detection of [M1Na] 1 ions. Oil samples exhibit quite unique TAG profiles, which are suitable for rapid characterization of the original plant oils. The fatty acid composition of the corresponding TAG structures was calculated using lipid analysis software based on the known fatty acid composition. Relative quantification of TAG components was in good agreement with the literature, in case appropriate data are available so far.

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Volatile fraction of neem oil as a spermicide

Cited by 53 publications

References 3 publications

Investigations of antioxidant and antibacterial activity of leaf extracts of Azadirachta indica

Investigations of antioxidant and antibacterial activity of leaf extracts of Azadirachta indica

Review on pharmacological and toxicologyical effects of oleum azadirachti oil

Volatile compounds and triacylglycerol composition of original Indian fatty plant oils

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