Visual Exploration Area in Neglect: A New Analysis Method for Video-Oculography Data Based on Foveal Vision

Kaufmann, Brigitte Charlotte; Knobel, Samuel E. J.; Nef, Tobias; Müri, René M.; Cazzoli, Dario; Nyffeler, Thomas

doi:10.3389/fnins.2019.01412

Cited by 17 publications

(16 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For the characterization and the allocation of the stroke patients, only one paper-pencil cancellation task was used. Future studies should aim to recruit a larger group of neglect patients and assess the neglect symptoms using several methods also including, e.g., eye-tracking (Kaufmann et al, 2020) and the assessment of neglect in the activities of daily living with the Catherine-Bergego Scale (Bergego et al, 1995).…”

Section: Limitations and Outlookmentioning

confidence: 99%

Immersive 3D Virtual Reality Cancellation Task for Visual Neglect Assessment: A Pilot Study

Knobel

Kaufmann

Gerber

et al. 2020

Front. Hum. Neurosci.

Self Cite

View full text Add to dashboard Cite

Background: Unilateral spatial neglect is an attention disorder frequently occurring after a right-hemispheric stroke. Neglect results in a reduction in quality of life and performance in activities of daily living. With current technical improvements in virtual reality (VR) technology, training with stereoscopic head-mounted displays (HMD) has become a promising new approach for the assessment and the rehabilitation of neglect. The focus of this pilot study was to develop and evaluate a simple visual search task in VR for HMD. The VR system was tested regarding feasibility, acceptance, and potential adverse effects in healthy controls and right-hemispheric stroke patients with and without neglect. Methods: The VR system consisted of two main components, a head-mounted display to present the virtual environment, and a hand-held controller for the interaction with the latter. The task followed the rationale of diagnostic paper-pencil cancellation tasks; i.e., the participants were asked to search targets among distractors. However, instead of a two-dimensional setup, the targets and distractors were arranged in three dimensions, in a sphere around the subject inside its field of view. Usability and acceptance of the task, as well as the performance in the latter, were tested in 15 right-hemispheric subacute stroke patients (10 of whom with and five of whom without unilateral spatial neglect; mean age: 67.1 ± 10.5 years) and 35 age-matched healthy controls. Results: System usability and acceptance were rated as high both in stroke patients and healthy controls, close to the maximum score of the questionnaire scale. No relevant adverse effects occurred. There was a high correlation (r = 0.854, p = 0.002) between the Center of Cancellation [an objective neglect measure) calculated from a paperpencil cancellation task (Sensitive Neglect Test (SNT)] and the newly developed VR cancellation task. Conclusion: Overall, the developed visual search task in the tested VR system is feasible, well-accepted, enjoyable, and does not evoke any significant negative effects, both for

show abstract

Section: Limitations and Outlookmentioning

confidence: 99%

Immersive 3D Virtual Reality Cancellation Task for Visual Neglect Assessment: A Pilot Study

Knobel

Kaufmann

Gerber

et al. 2020

Front. Hum. Neurosci.

Self Cite

View full text Add to dashboard Cite

show abstract

“…Finally, there was no difference between groups regarding the number of immediate revisits, whereas patients with VSN made more delayed revisits than patients without VSN. Revisiting targets can be explained by deficits in spatial working memory, often associated with VSN (Kaufmann et al, 2020;Mannan et al, 2005;Saj et al, 2020;Wansard et al, 2014).…”

Section: Discussionmentioning

confidence: 99%

How does the number of targets affect visual search performance in visuospatial neglect?

Brink

Elshout

Nijboer

et al. 2020

Journal of Clinical and Experimental Neuropsychology

View full text Add to dashboard Cite

Introduction: Impairments in visual search are a common symptom in visuospatial neglect (VSN). The severity of the lateralized attention bias in visual search tasks can vary depending on the number of distractors: the more distractors, the more targets are missed. However, little is known about how the number of targets affect search performance in VSN. The aim of the current study was to examine the effect of the number of targets on hit rate in VSN. Methods: We included 23 stroke patients with right-brain damage and VSN, 55 with right-brain damage without VSN, and 49 with left-brain damage without VSN, all admitted for inpatient rehabilitation. In a visual search task, patients had to find and tap targets, presented along with non-targets. The location and number of targets varied from trial to trial, allowing the evaluation of the effects of number and location of targets on hit rate. Results: VSN patients detected a lower percentage of targets when more targets were present. For patients with right-brain damage without VSN, adding targets only reduced the hit rate of the most contralesional target. No effect of number of targets on hit rate was seen in patients with left-brain damage. Additionally, VSN patients found less contralesional targets than ipsilesional targets, made more delayed revisits, and had an initial rightward bias when compared to the other groups. There were no differences in search time, search consistency, or immediate revisits between groups. There was a moderate positive relation between the hit rate asymmetry score in our search task and conventional paper-and-pencil VSN tasks, and neglect behavior in daily life. Conclusions: In VSN patients, a higher number of targets reduces the hit rate. The reduced hit rate in visual search evoked by additional targets should be taken into account when assessing visual search in VSN.

show abstract

“…Video-oculography was assessed by means of an FVE paradigm, as previously described ( Ptak et al, 2009 ; Cazzoli et al, 2011 ; Fellrath and Ptak, 2015 ; Paladini et al, 2019 ; Kaufmann et al, 2020a , b ). In short, naturalistic images (e.g., colored photographs of everyday scenes such as the view of a mountain or of a public place; size 1200 × 900 pixels), and their mirrored versions (mirrored along the vertical axis) were presented on a computer screen.…”

Section: Methodsmentioning

confidence: 99%

“…After stroke, neglect has been reported to occur in 43–80% of patients with a right-hemispheric lesion ( Stone et al, 1991 ; Azouvi et al, 2002 ; Ringman et al, 2004 ). Recent studies suggested that video-oculography may be an appropriate method to analyze visual neglect (visual exploration of naturalistic scenes, e.g., Delazer et al, 2018 ; Kaufmann et al, 2020a , b ; visual exploration of abstract imags, e.g., Mannan et al, 2005 ; visual exploration of faces, e.g., Van Belle et al, 2010a , b ; Verfaillie et al, 2014 ). Especially, a free visual exploration paradigm (FVE) might be a fast and accurate screening tool to detect neglect ( Delazer et al, 2018 ; Kaufmann et al, 2020a ).…”

Section: Introductionmentioning

confidence: 99%

Test-Retest-Reliability of Video-Oculography During Free Visual Exploration in Right-Hemispheric Stroke Patients With Neglect

et al. 2020

Self Cite

View full text Add to dashboard Cite

The Mean gaze position during free visual exploration (FVE) is a sensitive tool to detect neglect in patients after a right-hemispheric stroke. Here we investigated the test-retestreliability of mean gaze position during FVE in 23 patients with left-sided neglect after a first-ever sub-acute right-hemispheric stroke. We analyzed the reliability between different test sets administered within 11 days (test sets A and B, each including different images and their mirrored versions), and between repeated measures using the same test set administered three times within 2 days (test set C, including the same images and their mirrored versions). The intra-class correlation coefficient (ICC) showed good reliability between the two different test sets (test sets A and B; ICC = 0.819), and excellent reliability for the repeated measures with the same test set C (ICC = 0.964). FVE can therefore be recommended for the longitudinal assessments of patients' neglect severity during neurorehabilitation as well as in treatment trials.

show abstract

Visual Exploration Area in Neglect: A New Analysis Method for Video-Oculography Data Based on Foveal Vision

Cited by 17 publications

References 35 publications

Immersive 3D Virtual Reality Cancellation Task for Visual Neglect Assessment: A Pilot Study

Immersive 3D Virtual Reality Cancellation Task for Visual Neglect Assessment: A Pilot Study

How does the number of targets affect visual search performance in visuospatial neglect?

Test-Retest-Reliability of Video-Oculography During Free Visual Exploration in Right-Hemispheric Stroke Patients With Neglect

Contact Info

Product

Resources

About