Virtual non-contrast in second-generation, dual-energy computed tomography: Reliability of attenuation values

Toepker, Michael; Möritz, Thomas; Krauß, Bernhard; Weber, Michael; Euller, G.; Mang, Thomas; Wolf, Florian; Herold, Christian; Ringl, Helmut

doi:10.1016/j.ejrad.2011.12.011

Cited by 146 publications

(92 citation statements)

References 20 publications

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“…These were the greatest in the aorta, spleen, and fat; although present, the differences were below 15 HU in 95.5% of measurements. 37 Larger differences between the virtual and true unenhanced HU in the spleen and fat compared with other abdominal organs were also noted on portal-phase DSDE with the use of a tin filter on DSDE. 38 With the introduction of a new RSDE postprocessing material suppression technique called GSI VUE (General Electric Healthcare, Waukesha, WI) that uses a multimaterial decomposition to quantify then replace iodine fractional values with blood to create a monoenergetic image on which HUs are measurable, there is now capability to compare virtual unenhanced HU to conventional unenhanced HU on this scanner as well.…”

Section: Dual-energy Ct Evaluation Of Hepatic Fat Contentmentioning

confidence: 88%

Material Density Hepatic Steatosis Quantification on Intravenous Contrast-Enhanced Rapid Kilovolt (Peak)–Switching Single-Source Dual-Energy Computed Tomography

Patel

Kumbla

Berland

et al. 2013

Journal of Computer Assisted Tomography

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The RSDE milligram-per-milliliter fat values correlate well with hepatic steatosis defined by the L-S difference less than 1 on conventional MDCT. A threshold of 1027 mg/mL can identify 90% of steatotic livers when post-IV contrast RSDE is used, without obtaining additional CU scans. However, regression equations were not helpful to convert an individual participant's milligram-per-milliliter fat or milligram-per-milliliter water-derived from RSDE material density images to CU MDCT HU for the estimation of liver fat content.

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Section: Dual-energy Ct Evaluation Of Hepatic Fat Contentmentioning

confidence: 88%

Material Density Hepatic Steatosis Quantification on Intravenous Contrast-Enhanced Rapid Kilovolt (Peak)–Switching Single-Source Dual-Energy Computed Tomography

Patel

Kumbla

Berland

et al. 2013

Journal of Computer Assisted Tomography

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“…The low tube current of only 80 kV brings an inappropriate photon rate to the detectors in the abdomen and results in a low penetration depth and artifacts (26). With the novel technology of a tin filter for the 140-kV tube voltage, the x-ray spectra overlap between 100 kV and Sn140 kV is reduced (27,28). We scanned the spine with 100-and Sn140-kV tube voltages to reduce the artifacts, especially in patients with a large body mass index.…”

Section: Musculoskeletal Imaging: Bone Marrow Edema In Vertebral Compmentioning

confidence: 99%

Bone Marrow Edema in Vertebral Compression Fractures: Detection with Dual-Energy CT

Wang

Tsai

Chuang³

et al. 2013

Radiology

155

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Purpose:To assess the use of the dual-energy computed tomographic (CT) virtual noncalcium technique in the evaluation of bone marrow edema in vertebral compression fractures. Materials and Methods:This prospective study was approved by the institutional review board; informed consent was obtained from all patients. Sixty-three consecutive patients with 112 thoracic and/or lumbar vertebral compression fractures were studied between January 2011 and April 2012. All patients underwent both dual-energy CT (100 kV and Sn140 kV, where Sn indicates the use of a 0.4-mm tin filter) and magnetic resonance (MR) imaging. Dual-energy CT data were postprocessed by using a three-material decomposition algorithm for generating noncalcium images of the collapsed bodies. Two radiologists evaluated for the presence of abnormal attenuation alterations in the bone marrow by using color-coded maps and measured CT numbers on noncalcium grayscale images. Bone sclerosis and intravertebral air were evaluated with CT scans. MR images served as the reference standard. CT numbers were subjected to receiver operating characteristic curve analysis. Results:MR imaging depicted 46 edematous and 66 nonedematous vertebral compression fractures. Eighty-two bodies were classified as having less than 50% sclerosis and/or air. Significant differences in noncalcium CT numbers between edematous and nonedematous vertebral compression fractures were found for both readers (P , .0001).CT numbers for the diagnosis of bone marrow edema on the basis of MR imaging revealed areas under the receiver operating characteristic curve of 0.799 and 0.841 for readers 1 and 2, respectively (P = .56). Use of a cutoff value of 280 to differentiate edematous vertebral bodies resulted in a sensitivity of 96.3%, specificity of 98.2%, and accuracy of 97.6% in the group of vertebral bodies with less than 50% sclerosis and/or air. Conclusion:Dual-energy CT virtual noncalcium images were able to depict bone marrow in the collapsed vertebral bodies, especially in those with less than 50% sclerosis and/or air.q RSNA, 2013

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“…Dual-energy CT (DECT) can obtain different energy data to differentiate between various substances [12,13], which allows the removal of calcium from the resultant image. Virtual non-calcium (VNCa) image of the bone joint can display the bone marrow by means of subtracting of calcium using dual-energy algorithm [14][15][16][17].…”

Section: Introductionmentioning

confidence: 99%

Good interrater reliability of a new grading system in detecting traumatic bone marrow lesions in the knee by dual energy CT virtual non-calcium images

Cao

Wang

Kong

et al. 2015

European Journal of Radiology

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Virtual non-contrast in second-generation, dual-energy computed tomography: Reliability of attenuation values

Cited by 146 publications

References 20 publications

Material Density Hepatic Steatosis Quantification on Intravenous Contrast-Enhanced Rapid Kilovolt (Peak)–Switching Single-Source Dual-Energy Computed Tomography

Material Density Hepatic Steatosis Quantification on Intravenous Contrast-Enhanced Rapid Kilovolt (Peak)–Switching Single-Source Dual-Energy Computed Tomography

Bone Marrow Edema in Vertebral Compression Fractures: Detection with Dual-Energy CT

Good interrater reliability of a new grading system in detecting traumatic bone marrow lesions in the knee by dual energy CT virtual non-calcium images

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