Vesical nephrogenic adenoma: an unusual presentation of a bladder tumour

Martínez-Sanchiz, C.; Martínez-Ruiz, J.; Anguita-Fernandez, Pedro J.; Giménez-Bachs, José M.; Atienzar-Tobarra, Manuel; Rodríguez, J.A. Virseda; Salinas-Sánchez, Antonio S.

doi:10.5489/cuaj.11005

Cited by 3 publications

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“…Martínez-Sanchíz et al [ 45 ] reported 2 cases of nephrogenic adenoma of the urinary bladder with a history of transurethral resection of the bladder and the prostate and a history of prolonged voiding symptoms. In both cases, the findings of encysted tubular structures lined with flattened cuboidal cells without atypia were consistent with the diagnosis of nephrogenic adenoma of the urinary bladder.…”

Section: Results/literature Reviewmentioning

confidence: 99%

Nephrogenic Adenoma of the Urinary Bladder: A Review of the Literature

Venyo

2015

International Scholarly Research Notices

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Background. Nephrogenic adenoma of the urinary bladder (NAUB) is a rare lesion associated with nonspecific symptoms and could inadvertently be misdiagnosed. Aim. To review the literature. Methods. Various internet search engines were used. Results. NAUB is a benign tubular and papillary lesion of the bladder, is more common in men and adults, and has been associated with chronic inflammation/irritation, previous bladder surgery, diverticula, renal transplantation, and intravesical BCG; recurrences and malignant transformations have been reported. Differential diagnoses include clear cell adenocarcinoma, endocervicosis, papillary urothelial carcinoma, prostatic adenocarcinoma of bladder, and nested variant of urothelial carcinoma; most NAUBs have both surface papillary and submucosal tubular components; both the papillae and tubules tend to be lined by a single layer of mitotically inactive bland cells which have pale to clear cytoplasm. Diagnosis may be established by using immunohistochemistry (positive staining with racemase; PAX2; keratins stain positive with fibromyxoid variant), electron microscopy, DNA analysis, and cytological studies. Treatment. Endoscopic resection is the treatment but recurrences including sporadic malignant transformation have been reported. Conclusions. There is no consensus on best treatment. A multicentre study is required to identify the treatment that would reduce the recurrence rate, taking into consideration that intravesical BCG is associated with NAUB.

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Section: Results/literature Reviewmentioning

confidence: 99%

Nephrogenic Adenoma of the Urinary Bladder: A Review of the Literature

Venyo

2015

International Scholarly Research Notices

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Adenoma nefrogénico da bexiga: apresentação de caso clínico e revisão da literatura

Baltazar

Meirinha

João

et al. 2016

Acta Urológica Portuguesa

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Recurrence of childhood nephrogenic adenoma in urinary bladder developed four years after previous surgery despite intravesical sodium hyaluronate therapy

Özçift

Kaçar

Tiryaki

2016

Turkish Journal of Urology

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Nephrogenic adenoma (NA) is a rarely seen benign metaplastic lesion of the urinary tract. Its etiology is uncertain, but induced by chronic inflammation, irritation, and trauma. NA is located in the urinary tract, most commonly in the bladder. NA usually presents with hematuria and lower urinary tract symptoms. In the literature it is mostly seen in adults but about 30 cases of NA's have been reported in children. Treatment of intravesical lesions consists of transurethral resection (TUR) and fulguration and rarely partial or total cystectomy may be required in ineffective TUR. Recurrence rate is high during long-term follow-up. The intravesical application of sodium hyaluronate produces a protective effect on the glycosaminoglycan layer and delays or prevents its recurrence. We report a case of recurrent NA of the bladder in a pediatric male patient who was presented four years after previous surgery despite intravesical sodium hyaluronate therapy.

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Vesical nephrogenic adenoma: an unusual presentation of a bladder tumour

Cited by 3 publications

References 0 publications

Nephrogenic Adenoma of the Urinary Bladder: A Review of the Literature

Nephrogenic Adenoma of the Urinary Bladder: A Review of the Literature

Adenoma nefrogénico da bexiga: apresentação de caso clínico e revisão da literatura

Recurrence of childhood nephrogenic adenoma in urinary bladder developed four years after previous surgery despite intravesical sodium hyaluronate therapy

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