2008
DOI: 10.1007/s00431-008-0717-y
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Vertical transmission of HIV in Belgium: a 1986–2002 retrospective analysis

Abstract: Prophylactic interventions have lead to the reduction of the mother-to-child transmission (MTCT) of human immunodeficiency virus type 1 (HIV-1) to less than 2% in industrialized countries. The aim of this study was to evaluate the changes over time in vertical transmission according to the standard care of prophylaxis in the practice of a single large reference center and to identify the risk factors for failure. The rate of MTCT decreased progressively from 10% in 1986-1993 to 4.7% in 1999-2002, reflecting th… Show more

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Cited by 20 publications
(12 citation statements)
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References 18 publications
(10 reference statements)
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“…These rates found in Brazil are higher than those reported in studies published in Europe, where prophylactic measures are implemented early in pregnancy, resulting in mother-to-child transmission rates of around 1% [21][22][23][24][25] .…”
Section: Discussioncontrasting
confidence: 47%
“…These rates found in Brazil are higher than those reported in studies published in Europe, where prophylactic measures are implemented early in pregnancy, resulting in mother-to-child transmission rates of around 1% [21][22][23][24][25] .…”
Section: Discussioncontrasting
confidence: 47%
“…Preventive measures to reduce the risk for MTCT have been implemented over time according to published guidelines as previously described. 25 …”
Section: Prevention Of Mtct Of Hiv and Followup Of Exposed Infantsmentioning
confidence: 97%
“…However, the advent of available highly active antiretroviral therapy (HAART) in many sub-Saharan African countries has changed the situation for HIV-positive persons. HAART has been shown to drastically reduce the risk of MTCT of HIV: The risk of MTCT in Denmark was less than 1% in all HIV-positive women (all on HAART) who gave birth between 2000-2005, and 1.7% in a large reference center for pregnant HIV-positive women in Belgium [6,7]. Similarly, HAART has been found to reduce the risk of vertical transmission of HIV in sub-Saharan African countries.…”
Section: Introductionmentioning
confidence: 99%