Vertebral body replacement using patient-specific three–dimensional-printed polymer implants in cervical spondylotic myelopathy: an encouraging preliminary report

Amelot, Aymeric; Colman, Matthew W.; Loret, Jean-Edouard

doi:10.1016/j.spinee.2018.01.019

Cited by 42 publications

(32 citation statements)

References 18 publications

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“…31 More recently, the use of 3D printed vertebral body replacement (VBR) has been reported for cervical spondylotic myelopathy. 32 After undergoing anterior cervical corpectomy and decompression, 3D printed customized VBRs made of polyethyletherketone (PEEK) were implanted in 6 patients with degenerative cervical spine disease. Another popular application of 3DP is in designing interbody cages, where incorporation of both a porosity and surface roughness akin to natural bone has been associated with bone growth activity.…”

Section: Customized Implantsmentioning

confidence: 99%

Current status of 3D printing in spine surgery

Garg

Mehta

2018

Journal of Clinical Orthopaedics and Trauma

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Three-dimensional printing (3DP) is one of the latest tools in the armamentarium of the modern spine surgeon. The yearning to be more precise and reliable whilst operating on the spine has led to an interest in this technology which has claimed to achieve these goals. 3D printing has been used pre-operatively for surgical planning and for resident or patient education. It has also found its way to the operation theatre where it is used to fabricate customized surgical tools or patient-specific implants. Several authors have highlighted significant benefits when 3D printing is used for specific indications in spine surgery. Novel applications of this technology in spine surgery have also been described and though still in a nascent stage, these are important for this technology to sustain itself in the future. However, major limitations have also come to light with this technology in use. This article seeks to review the current status and applications of 3D printing in spinal surgery and its major drawbacks while briefly describing the essentials of the technology. It is imperative that the modern spine surgeon knows about this important innovation and when and how it can be applied to improve surgical outcomes.

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Section: Customized Implantsmentioning

confidence: 99%

Current status of 3D printing in spine surgery

Garg

Mehta

2018

Journal of Clinical Orthopaedics and Trauma

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“…These techniques are used to print ceramics (inkjet printing, [ 13,75,76,137–141 ] SLS), [ 25,142 ] polymers in powder‐form (SLS, [ 18,50,51,55,67,68 ] inkjet printing), [ 61,143 ] composites (SLS, [ 74 ] inkjet printing), [ 91 ] and metals (SLM, [ 97,99,100,107 ] DMLS, [ 17,20,105,106 ] EBM, Figure 2). [ 98,101–104 ] All types of materials can be printed using a laser since they can all be found in powder form and the laser has sufficient power to fuse all kinds of particles.…”

Section: Additive Manufacturing For Bone Regenerationmentioning

confidence: 99%

“…The other clinical trials found in load‐bearing sites are for applications in spine surgery (NCT02926391 (see Amelot et al. results), [ 68 ] NCT03018392, NCT03647501, NCT04086784 and NCT03761563).…”

Section: Translational Studies On Custom‐made Synthetic Bone Graftsmentioning

confidence: 99%

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Additive Manufacturing of Material Scaffolds for Bone Regeneration: Toward Application in the Clinics

Garot

Bettega

Picart

2020

Adv Funct Materials

128

105

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Additive manufacturing (AM) allows the fabrication of customized bone scaffolds in terms of shape, pore size, material type, and mechanical properties. Combined with the possibility to obtain a precise 3D image of the bone defects using computed tomography or magnetic resonance imaging, it is now possible to manufacture implants for patient‐specific bone regeneration. This paper reviews the state‐of‐the‐art of the different materials and AM techniques used for the fabrication of 3D‐printed scaffolds in the field of bone tissue engineering. Their advantages and drawbacks are highlighted. For materials, specific criteria, are extracted from a literature study: biomimetism to native bone, mechanical properties, biodegradability, ability to be imaged (implantation and follow‐up period), histological performances, and sterilization process. AM techniques can be classified in three major categories: extrusion‐based, powder‐based, and vat photopolymerization. Their price, ease of use, and space requirement are analyzed. Different combinations of materials/AM techniques appear to be the most relevant depending on the targeted clinical applications (implantation site, presence of mechanical constraints, temporary or permanent implant). Finally, some barriers impeding the translation to human clinics are identified, notably the sterilization process.

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“…The most commonly used material to create 3D fusion cages is titanium; poly-E-caprolactone, polyether ketone ketone (PEKK), and tantalum are the other products that can also be used. 41,42 When the structure of the cages formed using titanium was examined, it was observed that the Young's modulus of the created structure falls between the normal cortical and the spongy bone. In a titanium cage optimization study published by Lin et al, 43 Young's modulus values close to normal human bone values were achieved.…”

Section: Intraoperative Pedicle Screw Templatesmentioning

confidence: 99%

3D printing and spine surgery

Şenköylü

Daldal

Çetinkaya

2020

J Orthop Surg (Hong Kong)

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Rapid prototyping (RP), also known as three-dimensional printing (3DP), allows the rapid conversion of anatomical images into physical components by the use of special printers. This novel technology has also become a promising innovation for spine surgery. As a result of the developments in 3DP technology, production speeds have increased, and costs have decreased. This technological development can be used extensively in different parts of spine surgery such as preoperative planning, surgical simulations, patient–clinician communication, education, intraoperative guidance, and even implantable devices. However, similar to other emerging technologies, the usage of RP in spine surgery has various drawbacks that are needed to be addressed through further studies.

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Vertebral body replacement using patient-specific three–dimensional-printed polymer implants in cervical spondylotic myelopathy: an encouraging preliminary report

Cited by 42 publications

References 18 publications

Current status of 3D printing in spine surgery

Current status of 3D printing in spine surgery

Additive Manufacturing of Material Scaffolds for Bone Regeneration: Toward Application in the Clinics

3D printing and spine surgery

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