Venous Leg Ulcers: A Review of Published Assessment and Treatment Algorithms

Bernatchez, Stéphanie F.; Eysaman-Walker, Jill; Weir, Dot

doi:10.1089/wound.2020.1381

Cited by 21 publications

(8 citation statements)

References 61 publications

(135 reference statements)

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“…Reproduced (Adapted) with permission [ 20 ] under the terms of the Creative Commons CC‐BY 4.0 license. Copyright 2017, BMJ Publishing Group Ltd. Reproduced (Adapted) with permission [ 21 ] under the Creative Commons CC‐BY‐NC license. Copyright 2022, Mary Ann Liebert, Inc. Reproduced (Adapted) with permission [ 22 ] under the terms of the Creative Commons Attribution‐Non‐Commercial‐Share Alike 3.0 Unported.…”

Section: Chronic Wounds: a Worldwide Clinical Menacementioning

confidence: 99%

Updates on Recent Clinical Assessment of Commercial Chronic Wound Care Products

Sharma

Zhao

2023

Adv Healthcare Materials

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Impaired wound healing after trauma, disorders, and surgeries impact millions of people globally every year. Dysregulation in orchestrated healing mechanisms and underlying medical complications make chronic wound management extremely challenging. Besides standard‐of‐care treatments including broad spectrum antibiotics and wound‐debridement, novel adjuvant therapies are clinically tested and commercialized. These include topical agents, skin substitutes, growth factor delivery, and stem cell therapies. With a goal to overcome factors playing pivotal role in delayed wound healing, researchers are exploring novel approaches to elicit desirable healing outcomes in chronic wounds. Although recent innovations in wound care products, therapies, and devices are extensively reviewed in past, a comprehensive review summarizing their clinical outcomes is surprisingly lacking. Herein, this work reviews the commercially available wound care products and their performance in clinical trials to provide a statistically comprehensive understanding of their safety and efficacy. The performance and suitability of various commercial wound care platforms, including xenogeneic and allogenic products, wound care devices, and novel biomaterials, are discussed for chronic wounds. The current clinical evaluation will provide a comprehensive understanding of the benefits and drawbacks of the most‐recent approaches and will enable researchers and healthcare providers to develop next‐generation technologies for chronic wound management.

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Section: Chronic Wounds: a Worldwide Clinical Menacementioning

confidence: 99%

Updates on Recent Clinical Assessment of Commercial Chronic Wound Care Products

Sharma

Zhao

2023

Adv Healthcare Materials

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“…За відсутністю лікарської допомоги така патологія ускладнюється поверхневими тромбофлебітами, інфекцією м'яких тканин і трофічними розладами з утворенням трофічних виразок [1][2][3][4].…”

Section: вступunclassified

Dermatoplasty for decompensated forms of varicose veins and post-thrombotic syndrome

Русин

Павук

Ковальчук

et al. 2023

Modern Medical Technology

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Objective(s). In order to improve the results of the treatment of the decompensated form of varicose veins and post-thrombotic syndrome, taking into account the angiosomal theory and using VAC and Magott therapy of the recipient woundof the trophic ulcer, evaluate different methods of dermatoplasty depending on the depth and area of the lesion. Methods. In the surgical clinic of the regional hospital named after A. Novak, 174 patients with chronic venous insufficiency (CVI) in the stage of lecompensation were under our observation. According to the etiology of the disease, there were 76 patients with varicose desease (VD) (group I), 98 patients with PTS (group II), while 27 patients with PTS had trophic ulcers on both lower extremities. With a trophic ulcer (TU) diameter of up to 10 cm in the I group of patients, 42.1% had the depth of the lesion of the IIst, and in the patients of the IIa group, the depth of the lesion was the IIIrd. was observed in 51.4% of cases. In the 1st group (76) patients, TU was cleaned with the help of VAC therapy in 32 patients, Magott therapy was used in 18 patients. TcpO2 was measured in the angiosomes of the anterior tibial artery (APA), posterior tibial artery (PTA), and peroneal artery (PA), as the corresponding arteries participate in the perfusion of the corresponding skin-muscle flaps Results. Rejection (lysis) of the graft was observed in 5 (6.6%) patients of the 1st group, and only in patients with dermatoplasty using the vintage method. Graft lysis was observed in 4 (5.6%) patients of the IIa group, in two with the vintage method and in two with split graft transplantation. In the IIb group (both limbs affected), partial lysis of the transplanted perforated split graft was observed in three limbs (6%). No complications were observed when the tissue complex was transplanted freely. Conclusions. Free flaps are units of tissue that can be transplanted from the donor site to the recipient wound while maintaining its blood supply. Pieces can be classified by the type of blood supply, their tissue composition, the method of transplantation, or the orientation of the vessels. The concept of angiosomes and venosomes explains the blood supply to the recipient wound necessary for the viability of the flap. Various monitoring methods are used to monitor patients after surgery, including assessment of physiological parameters and auxiliary methods (dopplerography, transcutaneous and epidermal oximetry). Factors affecting the viability of transplants after surgery include: thorough surgical intervention, adequate immobilization after surgery, prevention of infection, and adequate vascularization of the recipient wound.

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“…Atendendo à cronicidade da lesão, o papel do enfermeiro é fulcral para facilitar o ajustamento mental às limitações e às mudanças daí decorrentes e para fornecer recursos e estratégias capazes de concorrer para a melhoria do seu bem-estar (BERNATCHEZ et al, 2022;. Destaca-se, a importância da educação das pessoas, do apoio psicológico e físico, que têm um impacto efetivo na qualidade de vida da qual depende a complexa e adequada adesão ao tratamento, com o intuito de reduzir o tempo de cicatrização e prevenir recidivas (REIS et al, 2013).…”

Section: Introductionunclassified