Various Extracts of Some Medicinal Plants as Inhibitors for Beta-lactamase Activity

Al-Hayanni, Huda S. A.; El-Shora, Hamed M.

doi:10.21123/bsj.2021.18.1.0047

Cited by 8 publications

(6 citation statements)

References 11 publications

(10 reference statements)

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“…Sophora flavescens root samples purchased from local markets in Baghdad city were identified by a botanist (specialist in plant taxonomy in the Department of Biology/College of Science for women. Aqueous extracts of S. flavescens root were prepared according to Al-Hayanni and El-Shora (2021). Soak the dried root powder (60 g) with 600 mL distilled water (DW) for 3 h. To create an aqueous extract, the extraction solutions were filtrated with filter paper (Whatman No.…”

Section: Preparation Of S Flavescens Root Aqueous Extractmentioning

confidence: 99%

Green synthesis of gold nanoparticles from Sophora flavescens extract and their antibacterial effect against some pathogenic bacteria

Alnuaimi¹,

AL-Hayanni²,

Aljanabi³

2023

MJM

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Aims:The current study was aimed to evaluate the antibacterial activity of biogenic synthesized golden nanoparticles from Sophora flavescens Aiton roots aqueous extract against multidrug-resistant (MDR) clinical bacterial isolates. Methodology and results:The green synthesis of gold nanoparticles (AuNPs) was accomplished using S. flavescens roots aqueous extract and examined using many accepted techniques. The antibacterial activity of S. flavescens extract and the aqueous AuNPs at concentrations (7% and 9%) ppm were investigated against two clinical MDR bacteria, including Gram-positive (Staphylococcus aureus) and Gram-negative bacteria (Pseudomonas aeruginosa). The findings demonstrate inhibitory activity against the selected MDR bacterial isolates for the aqueous extract of S. flavescens and the aqueous AuNPs noted by the significant decrease in the number of bacteria after treatment with highly significant differences (P≤0.01) compared to the untreated control. Conclusion, significance and impact of study: Sophora flavescens root extracts and their biosynthesized AuNPs with antibacterial activity may find broad applications in fighting MDR pathogenic bacteria and therapeutic manufacturing.

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Section: Preparation Of S Flavescens Root Aqueous Extractmentioning

confidence: 99%

Green synthesis of gold nanoparticles from Sophora flavescens extract and their antibacterial effect against some pathogenic bacteria

Alnuaimi¹,

AL-Hayanni²,

Aljanabi³

2023

MJM

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“…The results showed that the extracts have some oxidative activity and that this activity has a synergistic effect on the antioxidant effect of DPPH radical. The high contents of total phenolic, total flavonoid, and tannin compounds in H. salicornicum and Z. coccineum alcoholic extracts can contribute to important antioxidants because of the strong relationship between the concentration of the compounds (27) . The phenolic extraction and the effectiveness of antioxidants, which showed that these compounds are mostly to charge as they are effective antioxidants has a polar nature (28) .…”

Section: Discussionmentioning

confidence: 99%

Studying the Effect of Flavonoids Extracted from Haloxylon salicornium and Zygophilium coccinium Plants on Burn Healing in Diabetic White Rabbits

Naji¹,

Enaya²,

Malih³

2023

The Egyptian Journal of Hospital Medicine

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Background: The use of plant extracts is a successful way to treat many diseases. Desert plants are rich in many antioxidant compounds, so they have been used since ancient times in folk medicine. The most important of these compounds are flavonoids that contain in their composition an aromatic ring and an oxidative hydroxyl group, which resists the free radical compounds formed in affected tissue and neutralize the tissue to reach the state of recovery.Objectives: The study aims to find an effective treatment to prevent tissue damage in burns or wounds in diabetic patients. Materials and methods: Two plants were used in this study; Haloxylon salicornicum and Zygophyllum coccineum (after proving their antioxidant activity by DPPH assay, with different concentrations for both plants). Flavonoids were extracted from them, and they were used to treat burns in laboratory rabbits with diabetes. The incidence of infection was confirmed by histological and hematological studies. Then, we studied of the effect of using the treatment on some blood variables, hormones and antioxidants during the treatment period for the stability of their effectiveness for treatment. Results:The study proved the effectiveness of these compounds by accelerating the treatment period despite diabetes and getting fast and effective results. Conclusion: Flavonoids of H. coccineum and Z. coccineum proved a high effectiveness of treatment compared to chemotherapy and accelerated the healing period of the wound.

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“…and identified by the Department of Biology/ College of Science for women. Aqueous and ethanol extracts of the Sumac fruit were prepared according to (11,12). with some modifications: by drenching 50 g each of the dry grind plant materials in 500 ml of solvent (distilled water in aqueous extract) and in 250 ml of solvent (ethanol in alcohol extract) at room temperature for 48 hrs.…”

Section: Methodsmentioning

confidence: 99%

Antibacterial and antibiofilm effect of sumac (Rhus coriaria L) fruits extracts against some multidrug_resistant pathogenic bacteria

Alaamery¹

2022

JFacMedBagdad

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Abstract Background: The prevalence of multidrug-resistant bacteria and their contribution to increased morbidity and mortality due to the difficult-to-treat diseases caused by these bacteria, has demonstrated a need to develop and use alternative antimicrobial agents to control multidrug-resistant bacteria. There has been a growing interest in medicinal plants and herbs and their extracts as an alternative approach to discovering new antimicrobial compounds Materials and Methods: The sumac (Rhus coriaria L) plant was selected for this study, and aqueous and alcoholic extracts were prepared from its fruits. They were tested against four multi-antibiotic resistant bacterial isolates that produce biofilms ( Gram-positive and Gram-negative), namely Staphylococcus aureus, Enterococcus faecalis, Acinetobacter baumannii, and Pseudomonas aeruginosa which isolated from Iraqi patients with wounds and burns in Medical City hospitals. Results: The current study proved that the aqueous and alcoholic extract of sumac ( Rhus coriaria L ) fruit is effective as an antibacterial and anti-biofilm against the studied multidrug-resistant bacterial isolates at all tested concentrations with significant differences. The study also showed that the alcoholic extract is more effective as an anti-bacterial and anti-biofilm than the aqueous extract of the sumac. Conclusion: The current study provides valuable results for the use of extracts of medicinal plants and herbs, including sumac extracts, to treat pathogenic bacteria that have become more resistant to antibiotics. These plant extracts also contain natural compounds that can be used without causing any harmful effects on patients. Keywords: Antibacterial activity, Anti-biofilm activity, Multidrug-resistant bacteria, Rhus coriaria L., Sumac,

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Various Extracts of Some Medicinal Plants as Inhibitors for Beta-lactamase Activity

Cited by 8 publications

References 11 publications

Green synthesis of gold nanoparticles from Sophora flavescens extract and their antibacterial effect against some pathogenic bacteria

Green synthesis of gold nanoparticles from Sophora flavescens extract and their antibacterial effect against some pathogenic bacteria

Studying the Effect of Flavonoids Extracted from Haloxylon salicornium and Zygophilium coccinium Plants on Burn Healing in Diabetic White Rabbits

Antibacterial and antibiofilm effect of sumac (Rhus coriaria L) fruits extracts against some multidrug_resistant pathogenic bacteria

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