Green synthesis of gold nanoparticles from Sophora flavescens extract and their antibacterial effect against some pathogenic bacteria

Abstract

Aims:The current study was aimed to evaluate the antibacterial activity of biogenic synthesized golden nanoparticles from Sophora flavescens Aiton roots aqueous extract against multidrug-resistant (MDR) clinical bacterial isolates. Methodology and results:The green synthesis of gold nanoparticles (AuNPs) was accomplished using S. flavescens roots aqueous extract and examined using many accepted techniques. The antibacterial activity of S. flavescens extract and the aqueous AuNPs at concentrations (7% and 9%) ppm were investigated against two clinical MDR bacteria, including Gram-positive (Staphylococcus aureus) and Gram-negative bacteria (Pseudomonas aeruginosa). The findings demonstrate inhibitory activity against the selected MDR bacterial isolates for the aqueous extract of S. flavescens and the aqueous AuNPs noted by the significant decrease in the number of bacteria after treatment with highly significant differences (P≤0.01) compared to the untreated control. Conclusion, significance and impact of study: Sophora flavescens root extracts and their biosynthesized AuNPs with antibacterial activity may find broad applications in fighting MDR pathogenic bacteria and therapeutic manufacturing.

Evaluation of Copper Nanoparticle Synthesis by Fusarium oxysporum Antibacterial Activity Against Staphylococcus aureus

“…The maximum inhibition zones were 18 mm at a concentration of 500 µg/ml of CuCo 3 NPs, whereas the 11 mm minimum inhibition zones were 62.5 µg/ml of CuCo 3 NPs (Figure 15). The results obtained were identical to the previous study results [31,32,33,34]. These various inhibition diameter zones are a result of significant differences in interactivity between bacteria and Cu NPs.…”

Growth inhibition of Pseudomonas aeruginosa using products of some probiotic microorganisms and secondary metabolites of Commiphora myrrha extracts estimated by GC-MS technique

“…Some chemical tests were conducted to investigate active groups of Myrrh extracts, where alkaloids, saponins, phenols, tannins, flavonoids, resins, glycosides, coumarins, and pH were detected according to the method mentioned by Al-Hayanni et al 19 .…”