Varicella-Zoster Virus Prophylaxis with the Traditional Chinese Medicine <i>Radix Isatidis</i> (<i>Banlangen</i>) in Patients with Multiple Myeloma Treated with Bortezomib

Guo, Hongwei; Mao, Jingjue; Qian, Xifeng; Sun, Chao; Sun, Hongli

doi:10.1089/acm.2011.0386

Cited by 7 publications

(2 citation statements)

References 7 publications

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“…A.DC., Campanulaceae), Ziwan (Asteris Radix Et Rhizoma, Aster tataricus L.f., Asteraceae), Pengsha (Borax) and Bingpian (Borneolum, Cinnamomum camphora (L.) Presl, Lauraceae). Banlangen, a monarch medicine of BQ, has been shown to have a wide range of antiviral activities [7], such as against influenza virus [8], varicella-zoster virus [9], and respiratory syncytial virus [10]. Huangqin has also been reported to have antiviral activity, exemplified by the anti-H1N1 virus [11], coxsackievirus [12], and respiratory syncytial virus [13].…”

Section: Introductionmentioning

confidence: 99%

Efficacy of Ban-Qin-Fei-Re-Qing oral liquid on avian infectious bronchitis

Ma,

Gao,

Wang

et al. 2024

One Health Adv.

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Infectious bronchitis virus (IBV) can cause respiratory infections in animals that often lead to heavy losses for breeding industry. Ban-Qin-Fei-Re-Qing oral liquid (BQ), a Chinese herbal compound, has been used to treat infectious bronchitis (IB). This research aimed to assess the antiviral effect of BQ against IBV and elucidate the underlying mechanisms through bioinformatics analysis. The experiments designed in this study investigated how BQ inhibits IBV propagation in chicken embryos and enhances protective effects on chicken embryos. The findings indicated that, in comparison to the model group (untreated), the BQ-treated groups exhibited a significant protective effect on IBV-infected chicken embryos. Moreover, the groups administered medium or high doses of BQ demonstrated a superior protective effect compared to the group treated with a lower dose. In addition, even at a low dose (2.5 mL/L), BQ successfully treated IB in chickens. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses revealed that the differentially expressed genes were enriched in antiviral pathways, such as the JAK/STAT and type I interferon signaling pathways. In conclusion, the current study demonstrated that BQ has antiviral activity and plays an antiviral role through the combined action of multiple antiviral pathways. These findings could lead to future research on identifying drugs to prevent and treat IB.

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Section: Introductionmentioning

confidence: 99%

Efficacy of Ban-Qin-Fei-Re-Qing oral liquid on avian infectious bronchitis

Ma,

Gao,

Wang

et al. 2024

One Health Adv.

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“…Banlangen (Radix Isatidis) is an official herbal medicine with the part of anti-virus, anti-endotoxin, antiinflammatory and improve immune system and grows in various parts of China (Chen et al, 2011;Du et al, 2013;Li and Yang, 2014). Studies have shown that the drawing material of R. Isatidis had a strong effect as antiviral, and which is often used in preventing virus or bacterial infection in clinical practice, and therefore, the R. Isatidis is considered to prevent diseases of pestilent maculae, fever headache, swollen-head infection, scarlet fever, pharyngitis, chicken pox, measles,hepatitis and flu (Huang, 2009;Guo et al, 2011;Xiao et al, 2014;Chen et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

Environmental factors affecting growth and development of Banlangen (Radix Isatidis) in China

Gang¹,

Wang²,

Xiang³

et al. 2015

Afr. J. Plant Sci.

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Banlangen (Radix Isatidis) is an herbal medicine, and grows in various parts of China. It can be classified into North Radix Isatidis and South Radix Isatidis. With the rising demand of users all over the world, more and more popularly used herbal plants are now grown in agricultural fields. The natural force of supply and demand has encouraged the cultivation of Banlangen in China. However, the cultivation of Banlangen at a large scale does not always result in high yield and good quality, because many agronomic factors have an influence on the growth of Banlangen, such as variety, soil properties, climate and other environmental factors. This paper provides a brief review on the progresses of recent research regarding agronomic factors that affect the growth and quality of Banlangen in China and elsewhere.

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Qualitative and quantitative analysis of glucosinolates and nucleosides in Radix Isatidis by HPLC and liquid chromatography tandem mass spectrometry

Wang¹,

Xie²,

Hu³

et al. 2013

Acta Pharmaceutica Sinica B

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Multi-component fingerprinting and quantitation of the glucosinolates and nucleosides in samples of Radix Isatidis have been carried out using high-performance liquid chromatography with diode-array detection and electrospray ionization tandem mass spectrometry (HPLC-DAD-ESI/MS). Five nucleosides together with one glucosinolate were identified by comparing retention times, ultraviolet spectra, mass spectra and/or empirical molecular formulae of reference compounds. Quantitation of these six compounds was carried out simultaneously by HPLC on a Phenomenex Luna C18 column using gradient elution with methanol and water and detection at 254 nm. All calibration curves were linear (r40.9994) within test ranges. Limits of detection and quantitation were 0.33 ng and 2.50 ng on column, respectively. Intra-and inter-day precision (as relative standard deviation) for all analytes was o2.19% with recoveries in the range 99.6%-101.8% at three concentration levels. The validated method was successfully applied to fingerprinting and assay of 25 batches of Radix Isatidis sourced from different geographical regions of China. The method is simple and reliable and has potential value in the quality control of Radix Isatidis.

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Varicella-Zoster Virus Prophylaxis with the Traditional Chinese Medicine Radix Isatidis (Banlangen) in Patients with Multiple Myeloma Treated with Bortezomib

Cited by 7 publications

References 7 publications

Efficacy of Ban-Qin-Fei-Re-Qing oral liquid on avian infectious bronchitis

Efficacy of Ban-Qin-Fei-Re-Qing oral liquid on avian infectious bronchitis

Environmental factors affecting growth and development of Banlangen (Radix Isatidis) in China

Qualitative and quantitative analysis of glucosinolates and nucleosides in Radix Isatidis by HPLC and liquid chromatography tandem mass spectrometry

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