Vapor‐controlled thin‐layer chromatography on reversed‐phase layers

Abstract

The chromatographic behavior of some hydrocarbons and some of their nitro derivates after preconditioning with solvent vapors has been investigated. After preloading with cyclohexane or hexane an improved separation of some sample pairs is observed. Furthermore, inversion of Rf values takes place. The preloading of the reversed-phase plates permits utilization of mobile phase with higherwater content, thus leading to a significant shortening of developing time.