Validity of Self-Reported Diagnosis of Osteoporosis in Japan Nurses’ Health Study

Kurabayashi, Takumi; Ideno, Yuki; Nagai, Kazue; Maruoka, Naho; Takamatsu, Kiyoshi; Hayashi, Kyozo

doi:10.2147/clep.s304939

Cited by 3 publications

(4 citation statements)

References 17 publications

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“…The difference may be that they used fracture incidence, whereas we used fracture prevalence. The reliability of self-reported information may be a problem because errors can be introduced [27], but also national fracture registries have flaws. Optimally, self-reported fractures should be checked against fracture registries, but it was not possible at the time.…”

Section: Discussionmentioning

confidence: 99%

Mandibular cortical bone structure as risk indicator in fractured and non-fractured 80-year-old men and women

2021

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Objective To investigate the association between mandibular cortex parameters and fracture in a group of 286 men and women, 79–80 years of age. Study design In a cross-sectional study, the mandibular cortex was evaluated with Klemetti’s index for cortical erosion. The cortical thickness was measured with a ruler adjusting for the magnification factor. The odds ratio (OR) for fracture when having a severely eroded cortex or a cortex thickness < 3 mm was calculated. Results A normal cortex was found in 65% of men, whereas only 7% had a severely eroded cortex. The OR for severely eroded cortex as fracture risk predictor was significant (2.32; 95% CI 1.3–4.2), also when the female group was evaluated separately. A significant difference was found between the mean thickness for men (3.96 mm) and women (2.92 mm), respectively. The OR for cortical thickness < 3 mm was significant (2.00; 95% CI 1.1–3.6) in the total group, but not when men and women were evaluated separately. Conclusions Among old women, the cortical parameters were significantly associated with prevalent fracture. In old men, other circumstances may be more important.

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Section: Discussionmentioning

confidence: 99%

Mandibular cortical bone structure as risk indicator in fractured and non-fractured 80-year-old men and women

2021

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“…First, because information regarding the diagnosis of osteoporosis and the incidence of fracture was based on participants’ self-reporting, there might be recall bias. The validity of self-reported versus objectively diagnosed osteoporosis has been considered a problem, and several studies have investigated this issue 28,29 . While one study showed relatively high consistency between self-reporting and objectively diagnosed osteoporosis in the incidence of osteoporosis in Japanese nurses, 28 poor agreement was reported in another study 29 …”

Section: Discussionmentioning

confidence: 99%

“…The validity of self-reported versus LIFESTYLE FACTORS, OSTEOPOROSIS, AND FRACTURE objectively diagnosed osteoporosis has been considered a problem, and several studies have investigated this issue. 28,29 While one study showed relatively high consistency between self-reporting and objectively diagnosed osteoporosis in the incidence of osteoporosis in Japanese nurses, 28 poor agreement was reported in another study. 29 Second, the lack of information regarding when osteoporosis and fracture were detected, as well as the cause of fracture, makes it difficult to interpret the results, especially in Group 4, in which both osteoporosis and fracture occurred during the follow-up period.…”

Section: Limitationsmentioning

confidence: 98%

Association of lifestyle factors with osteoporosis and fracture in postmenopausal women: a Japanese cohort study

Otonari

Ikezaki

Furusyo³

et al. 2021

Menopause

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Objective: Osteoporosis is a major risk factor for fracture later in life; however, few studies have examined the association of lifestyle factors with osteoporosis and fracture. This study aimed to identify factors associated with osteoporosis and fracture in postmenopausal women.Methods: We evaluated the association between baseline characteristics and outcomes (diagnosis of osteoporosis or incidence of fracture) in 4,427 postmenopausal women who participated in the Kyushu University Fukuoka Cohort Study on lifestyle-related diseases (baseline: February 2004 to August 2007; follow-up: February 2010 to December 2012). Among the women, 626 were diagnosed as having osteoporosis without a fracture, 294 sustained a fracture without a diagnosis of osteoporosis, and 137 were diagnosed with both osteoporosis and fracture during the average 5.3-year follow-up period; the remaining 3,370 participants were not diagnosed with osteoporosis or did not sustain a fracture. The association between lifestyle factors and the occurrence of osteoporosis and fracture was evaluated using logistic regression analysis.Results: Skipping breakfast was associated negatively with osteoporosis without fracture (odds ratio [OR] ¼ 0.40, P ¼ 0.009) but positively with fracture without osteoporosis (OR ¼ 2.30, P ¼ 0.0009). Glycated hemoglobin A1c levels were associated negatively with osteoporosis without fracture (OR ¼ 0.81, P ¼ 0.0003) but positively with fracture without osteoporosis (OR ¼ 1.18, P ¼ 0.03). Parental history of fracture and extraversion personality trait were both associated with fracture without osteoporosis.Conclusions: Osteoporosis and fracture showed different association patterns with lifestyle factors, and no factors were correlated with an increase in both osteoporosis and fracture.

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“…Nevertheless, a recent systematic review, as well as a recent social media survey of PLO, investigated only vertebral fractures [ 14 , 15 ]. In Japan, a few epidemiological studies of osteoporosis in young women have recently been published [ 13 , 16 ], but it is difficult to identify the occurrence of fragility fractures without major trauma in large populations with high anonymity. Toba et al [ 13 ] investigated the epidemiology of PLO using the Japanese Diagnostic Procedure Combination (DPC) database covering about half of all inpatients in Japan, but single fragility fractures are often treated without hospitalization.…”

Section: Introductionmentioning

confidence: 99%

Pregnancy and lactation-associated osteoporosis as a major type of premenopausal osteoporosis: a retrospective cohort study based on real-world data

Kasahara,

Tanaka-Mizuno,

Tsuji

et al. 2024

BMC Pregnancy Childbirth

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Background Pregnancy and lactation-associated osteoporosis (PLO), as well as premenopausal osteoporosis, might be a predictor of future fracture. This study aimed to describe the clinical features of PLO as a subtype of premenopausal osteoporosis and to evaluate medical interventions for it. Methods From an administrative claims database including 4,224,246 people in Japan, we classified women for whom the date of childbirth had been defined and who had suffered low-trauma fracture between the ages of 18–47 years as the premenopausal osteoporosis group. A fracture site for which the odds ratio for fractures occurring between 5 months before and 12 months after childbirth (around childbirth) was greater than 1 was considered the PLO site. We classified patients with a fracture at the PLO site around childbirth as the PLO group. The control group consisted of 500 women without fragility fractures. We investigated some drugs and diseases to explore fracture-causing factors, as well as medical interventions such as osteoporosis diagnosis, bone densitometry, anti-osteoporosis pharmacotherapy, and lactation inhibitors. Results In total, 231 parous women were classified into the premenopausal osteoporosis group. The most common fracture was vertebral fracture and was likely to occur around childbirth, followed by distal radius and sacral fractures, which were rare around childbirth. Considering vertebral, pelvic, and proximal femoral fractures as PLO sites, 56 women with 57 PLO fractures were classified into the PLO group. The incidence of PLO was estimated at 460 per million deliveries. Ovulation disorder and high maternal age were associated with the development of PLO. Vertebral fracture was the most common PLO fracture. It was mainly diagnosed a few months, and possibly up to 1 year, postpartum. PLO patients with vertebral fractures underwent more medical interventions than did those with other fractures, but they were still inadequate. Conclusions PLO with vertebral fracture was one of the major types of premenopausal osteoporosis. The prevalence of PLO is considered to be higher than previously thought, indicating the presence of potentially overlooked patients. More timely interventions for PLO might lead to the improved management of latent patients with premenopausal osteoporosis and reduce future fracture risk.

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Validity of Self-Reported Diagnosis of Osteoporosis in Japan Nurses’ Health Study

Cited by 3 publications

References 17 publications

Mandibular cortical bone structure as risk indicator in fractured and non-fractured 80-year-old men and women

Mandibular cortical bone structure as risk indicator in fractured and non-fractured 80-year-old men and women

Association of lifestyle factors with osteoporosis and fracture in postmenopausal women: a Japanese cohort study

Pregnancy and lactation-associated osteoporosis as a major type of premenopausal osteoporosis: a retrospective cohort study based on real-world data

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