Validation of the fullPIERS model for prediction of adverse outcomes in preeclampsia at a referral center

Guida, José Paulo; Cralcev, Christopher; Santos, Juliana Costa; Marangoni‐Junior, Marcos; Sanchez, Mariana Peccia; Costa, Maria Laura

doi:10.1016/j.preghy.2020.11.013

Cited by 7 publications

(2 citation statements)

References 12 publications

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“…We demonstrated that the fullPIERS model has good predictive power for maternal adverse events in pre‐eclampsia (AUC‐ROC 0.843, 95% CI 0.789–0.897) (Figure 3). This corroborated the results of Akkermans et al 18 and others, who not only externally validated the model's performance, but also reported its usefulness in cases of early‐onset pre‐eclampsia 17–24 . Notwithstanding, some of these studies were designed for high‐income countries.…”

Section: Discussionsupporting

confidence: 87%

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Prediction of complications of pre‐eclampsia using the fullPIERS high risk predictive model

Sharma

Suri

Khanam

et al. 2023

Intl J Gynecology & Obste

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ObjectiveTo determine the predicted probability percentage of complications in women with pre‐eclampsia using the Pre‐eclampsia Integrated Estimate of Risk (fullPIERS) model within the first 24 h after admission and assess the model's predictive value for complications of pre‐eclampsia.MethodsThis was a prospective cohort study in which the fullPIERS model was applied to 256 pregnant women with pre‐eclampsia within the first 24 h after admission. These women were then followed for 48 h to 7 days for maternal and fetal complications. Reciever operating characteristics (ROC) curves were generated to assess the performance of the fullPIERS model for adverse outcomes of pre‐eclampsia.ResultsOf the 256 women enrolled in the study, 101 women (39.5%) developed maternal complications, 120 women (46.9%) developed fetal complications, and 159 women (62.1%) developed both. With an area under the ROC curve of 0.843 (95% confidence interval 0.789–0.897), the fullPIERS model had good discriminating ability to predict complications at any time point between 48 h and 7 days after admission. The sensitivity and specificity of the model at a ≥5.9% cut‐off value for predicting adverse maternal outcomes were 60% and 97%, respectively; they were 44% and 96%, respectively, for predicting combined fetomaternal complications with a cut‐off value of 4.9%.ConclusionsThe fullPIERS model performs reasonably well in predicting adverse maternal and fetal outcomes in women with pre‐eclampsia.

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Section: Discussionsupporting

confidence: 87%

“…This corroborated the results of Akkermans et al 18 and others, who not only externally validated the model's performance, but also reported its usefulness in cases of early-onset pre-eclampsia. [17][18][19][20][21][22][23][24] Notwithstanding, some of these studies were designed for high-income countries.…”

Section: Discussionmentioning

confidence: 99%