Vaginal fibrosarcoma in a cow

Musal, Bayazit; Ulutaş, Pınar Alkım; Aydoğan, Ahmet

doi:10.1186/2046-0481-60-7-424

Cited by 14 publications

(23 citation statements)

References 3 publications

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“…There was no complication observed in the cow after the surgical operation. Various studies have reported no complication or metastasis after the surgical removal of vaginal tumors such as fibrosarcoma (3,6).…”

Section: Resultsmentioning

confidence: 99%

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Vaginal Fibrosarcoma in a Brown Swiss Cow

Kuru¹

2016

Atatürk Üniversitesi Veteriner Bilimleri Dergisi

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Absract:The presented case includes the vaginal fibrosarcoma hanging out through the lips of vulva of a 3-year old, brown Swiss cow and removal of the mass with operative intervention. In the clinical examination of the cow, no disorder other than the mass was detected. A hemorrhagic, necrotic, lobular mass spreading to various regions of vagina and hanging out through the lips of vulva was identified in clinical examination. The mass with the diameter of 15 x 12.5 x 13 cm was removed from the site by operative intervention. Histopathological and immunohistochemical examinations revealed that the mass was vaginal fibrosarcoma. The cow has been followed up for 6 months postoperatively. No complication or recurrence was observed. In conclusion, we believe that the vaginal fibrosarcoma in the presented case which was diagnosed as a result of histopathological and immunohistochemical examinations in a -3 year old cow will contribute to the scientific literature.

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Section: Resultsmentioning

confidence: 99%

“…The tumor can exhibit mushroom-shaped growth and can spread over a large area and can hang out of the vulva lips (3,4). A study performed on the prevalence of vaginal and vulvar tumors in dairy cows (n=1.100)…”

Section: Introductionmentioning

confidence: 99%

Vaginal Fibrosarcoma in a Brown Swiss Cow

Kuru¹

2016

Atatürk Üniversitesi Veteriner Bilimleri Dergisi

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“…Neoplasias no trato genital causam prejuízos à criação de bovinos pelas perdas reprodutivas e também pelo descarte desses animais [21]. Os principais tumores já diagnosticados afetando a vagina de vacas são aqueles originários de tecido conectivo -fibromas, fibropapilomas e fibrossarcomas -e de tecido muscular -leiomioma e leiomiossarcoma [6,8,10,15,16,21]. Em vacas que desenvolvem a forma multicêntrica da leucose bovina, células neoplásicas podem estar presentes no útero [7,11] formando nódulos ou massas, e menos frequentemente na vagina [11].…”

Section: Discussionunclassified

Hemolytic Crisis in a Dog with Copper-Associated Chronic Hepatitis

Mazaro

Luz

Herbichi

et al. 2019

Acta Scientiae. Vet.

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Background: Skin tumors are the most common neoplasia in veterinary medicine and squamous cell carcinoma (SCC) is the most frequent. In cattle, it is the main tumor besides linfosarcoma and normally affects taurine cattle, but is rare in Nelore cattle. SCC mainly affects mucocutaneous junctions such as the eyelids, sclera, vulva, and perineum, and has already been described in vagina, eye, and periocular tissues, in addition to the superior digestive tract. The purpose of this paper is to describe a vaginal squamous cell carcinoma in a Nelore cow. Case: A 10-year-old Nelore cow, used as an embryo donor, was submitted to a necropsy procedure. Clinically, the animal had prolonged recumbency, anorexia, weight loss, and vaginal discharge. There was a history of recurrent vaginal prolapses and an intraluminal vaginal mass that had grown over two years. At necropsy, there was diffuse fibrinous peritonitis with marked intestinal adhesions; the vagina was markedly expanded and measured 40 × 20 cm due to the presence of an intraluminal mass occupying the vestibulum and extending up to the cervix. In the vaginal lumen, there was large amount of fibrinonecrotizing malodorous material; the vaginal wall was thickened by an unencapsulated and poorly delimited, firm and white mass composed of sheets and nests of epithelial cells from the squamous layer surrounded by abundant fibrovascular stroma. The neoplastic cells were polygonal with marked pleomorphism, anisokaryosis, and anisocytosis; abundant eosinophilic and well-defined cytoplasmic borders. Sometimes it was possible to see desmosomes. The nuclei were rounded to oval with sparse chromatin and one or more nucleoli were seen. Mitotic figures were frequent (at least 3 per higher power field) and there were also a few multinucleated cells. Frequently, there was the formation of distinct keratin "pearls". Discussion: SCC frequently occurs in the skin, eyes, and vulva in cattle, since these are sites that lack pigment within the epidermis and have prolonged exposed to ultraviolet light. Vaginal SCC has already been described in one cow with recurrent vaginal prolapses that was submitted to follicular aspiration. In a survey of cattle tumors, most genital tract neoplasias affected the uterus, and vaginal tumors normally originated from connective tissue -fibromas, fibropapillomas, and fibrosarcoma -or muscular tissue -leiomyoma and leiomyosarcoma. Irreversible changes in cellular DNA can occur due to physical or chemical carcinogens, and also chronic inflammation. The cow in this paper was frequently submitted to follicular aspiration and this can cause chronic inflammation in the vaginal mucosa after the puncture and, when it's chronic, can represent one of the main initiating factors for tumor development. This cow's death was caused by diffuse and marked peritonitis. The same cause was previously described in cows submitted to follicular aspiration and, in one of these animals, there was a rectal perforation caused by mistakes during the procedure. In this animal, we did not...

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“…The relatively abundant connective tissue component identifi ed by Masson's trichrome staining is consistent for smooth muscle tumors of the genital tract (COOPER & VALENTINE, 2002). Although other tumors such as fi broma or fi brosarcoma would also have abundant collagenous matrix, the tumor cells would lack myogenic differentiation (MUSAL et al, 2007;HAMALI & ASHRAFIHELAN, 2010). IHC staining showed variation in the immunoreactivity of the neoplastic cells to SMA and desmin, but the internal controls (vascular smooth muscle) in both cases validated the effi ciency of each assay.…”

Section: No Presente Trabalho Foram Descritos Os Achados Clínicos Pmentioning

confidence: 90%

“…Previously described reports of tumors arising from the vagina of the cow include fi broleiomyoma (TIMURKAAN et al, 2009), fi broma (ANDERSON & SANDISON, 1969, fi brosarcoma (MUSAL et al, 2007;HAMALI & ASHRAFIHELAN, 2010), and fi broleiomyosarcoma (AVCI et al, 2010); a cervical leiomyoma is also described within the reproductive tract of a cow (SENDAG et al, 2008). Within the female genitalia of domestic animals, vaginal leiomyoma is the most frequently occurring neoplasm particularly in the bitch (MCLACHLAN & KENNEDY, 2000) while leiomyosarcomas are considered uncommon lesions (SCHLAFER & MILLER, 2007 A 12-year-old, Senepol breed of cow that is used exclusively for embryo transfer (ET) and in-vitro fertilization (IVF) was brought to the Veterinary Teaching Hospital, Universidade Federal de Uberlândia, Minas Gerais, Brazil, in June 2010 after surgical excision of a mass from the vaginal region was done at a private veterinary clinic, due to prolapse of the cervical-vaginal area.…”

Section: No Presente Trabalho Foram Descritos Os Achados Clínicos Pmentioning

confidence: 99%