Vaccine distribution chains in low- and middle-income countries: A literature review

Boeck, Kim De; Decouttere, Catherine; Vandaele, Nico

doi:10.1016/j.omega.2019.08.004

Cited by 67 publications

(51 citation statements)

References 87 publications

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“…Research in one of developed Europe countries, shows that only one-third of the refrigerators fulfilled the cold chain requirements, and more than 15% threatening vaccine potency [10]. There is a gap of cold chain equipment providing a promising avenue for new technological research [6,11]. This research proposed reliable vaccine storage to support the cold chain especially in remote and rural area.…”

Section: Vaccine Cold Chainmentioning

confidence: 97%

Design of Solar Powered Vaccine Backpack

Satria¹,

Jaenul²,

Gamayel³

2021

Atlantis Highlights in Engineering

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Pandemic effects rural and indigenous area that is hard and far to reach by vehicles. Most of the medical deliveries to this remote area is done on foot and taken days to reach destination. Vaccine consistency is affected by their ambient temperature and duration of exposure to adverse temperature in their deliveries. In this research, the development of a reliable personnel backpack that provides self-sustainable energy for vaccine cold storage is proposed. This vaccine storage should support the ambient and stable temperature with at least between 2° -8° Celsius. The problem on the transportation infrastructure in rural and remote area need to be addressed. Most of delivery is done by foot through the jungle or footpath that cannot be crossed by vehicles. Multi modal of power source is needed to accommodate the lack of electricity along the route in rural and remote area. Ergonomics and lightweight are also important for the personnel to bring the vaccine.

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Section: Vaccine Cold Chainmentioning

confidence: 97%

Design of Solar Powered Vaccine Backpack

Satria¹,

Jaenul²,

Gamayel³

2021

Atlantis Highlights in Engineering

View full text Add to dashboard Cite

show abstract

“…A review of the vaccine distribution literature shows the research in this field is in its infancy. Some researchers, such as De Boeck et al (2019) and Corey et al (2020), have studied strategic and managerial approaches to vaccine distribution. Other researchers such as Gamchi et al (2020), Yang et al (2020), and Rastegar et al (2021) have proposed mathematical models for vaccine distribution and supply chain network optimization.…”

Section: Motivation and Contributionsmentioning

confidence: 99%

“…They categorized these studies into the product, production, allocation, and distribution modeling groups by combining the WHO's priorities for creating a robust and flexible vaccine supply chain with an operations research perspective. Similarly, De Boeck et al (2019) studied the vaccine distribution studies in low-and middle-income countries. They identified several problems that had received little or no attention in the operations research literature.…”

Section: Introductionmentioning

confidence: 99%

A mathematical programming approach for equitable COVID-19 vaccine distribution in developing countries

et al. 2021

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Developing countries scramble to contain and mitigate the spread of coronavirus disease 2019 (COVID-19), and world leaders demand equitable distribution of vaccines to trigger economic recovery. Although numerous strategies, including education, quarantine, and immunization, have been used to control COVID-19, the best method to curb this disease is vaccination. Due to the high demand for COVID 19 vaccine, developing countries must carefully identify and prioritize vulnerable populations and rationalize the vaccine allocation process. This study presents a mixed-integer linear programming model for equitable COVID-19 vaccine distribution in developing countries. Vaccines are grouped into cold, very cold, and ultra-cold categories where specific refrigeration is required for their storage and distribution. The possibility of storage for future periods, facing a shortage, budgetary considerations, manufacturer selection, order allocation, time-dependent capacities, and grouping of the heterogeneous population are among the practical assumptions in the proposed approach. Real-world data is used to demonstrate the efficiency and effectiveness of the mathematical programming approach proposed in this study.

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“…Thus, simulation has more advantages in the processes where the demands and other parameters change over time. In supply chain and logistics, simulation can be used to validate the solutions obtained by optimization models ( De Boeck et al, 2018 , Sun et al, 2019 , Yu et al, 2021 ). For example, Dai, et al ( Dai et al, 2020 ) used a numerical simulation to test their decision-making time-delay model for vaccine transportation.…”

Section: Literature Reviewmentioning

confidence: 99%

“…In an international vaccine supply chain, the vaccines from foreign sources arrive in a country by air or by sea and are stored in a central warehouse before being further transported to the rest of the country through intermediate distribution centers ( Lim et al, 2019 ). The vaccine distribution at the country level can be broken down into four stages: (1) the sourcing at the national level; (2) the storage of vaccines; (3) the transportation between different levels, and (4) the administration of vaccines ( De Boeck et al, 2018 ). The decisions on these four stages can be analyzed by computer-based simulation tools, e.g., HERMES, AnyLogic, etc.…”

Section: Literature Reviewmentioning

confidence: 99%

A simulation-based analysis for effective distribution of COVID-19 vaccines: A case study in Norway

Sun

Andoh

2021

Transportation Research Interdisciplinary Perspectives

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Since December 2020, the vaccines from several manufacturers, e.g., Pfizer/BioNTech, Moderna, etc., have been approved for mass vaccination to control the COVID-19 pandemic, which has caused more than 100 million infections and 2.4 million deaths. These vaccines are produced and transported in large quantities to suffice the needs of several countries. Before arriving at the end-users, the vaccines need to be stored at extremely low temperatures and distributed through reliable cold chain logistics networks. Thus, the timely and cost-effective distribution of COVID-19 vaccines via cold chain logistics has become a complex operational challenge. In this paper, we develop a simulation-based approach combining both route optimization and dynamic simulation to improve the logistics performance for COVID-19 vaccine distribution. A state-of-the-art simulation package called anyLogistix is used to perform a real-world case study in Norway. With the data of periodic vaccine demands, customer and warehouse locations, vehicle-related costs and emissions, and expected service levels, implications are obtained based on the analysis of several scenarios. Our experimental results reveal that the service level, cost-effectiveness, environmental performance, and equity of a cold chain vaccine logistics system can be significantly influenced by the fleet size, the fleet composition, the type of vehicle used, and the route optimization. Thus, these factors need to be holistically considered in the planning of an effective COVID-19 vaccine distribution system.

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Vaccine distribution chains in low- and middle-income countries: A literature review

Cited by 67 publications

References 87 publications

Design of Solar Powered Vaccine Backpack

Design of Solar Powered Vaccine Backpack

A mathematical programming approach for equitable COVID-19 vaccine distribution in developing countries

A simulation-based analysis for effective distribution of COVID-19 vaccines: A case study in Norway

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