Vaccination studies for the control of campylobacteriosis in Jamaican cattle

Abstract

Following the first diagnosis of campylobacteriosis in Jamaican cattle a field study was undertaken to determine the pathogenicity of Campylobacter fetus subspecies venerealis Jam (Jamaican strain) and to evaluate the effectiveness of vaccination in controlling the disease. A total of 46 nonpregnant yearling heifers and four two-year-old bulls were used in two separate experiments. The results showed that C fetus subspecies venerealis Jam readily colonised the reproductive tract of susceptible heifers and persisted in some animals (68 per cent of unvaccinated and 33 per cent of vaccinated animals) for the duration of the experiment. Pregnancy was confirmed in 13 of 18 (72 per cent) culture-negative heifers but in only eight of 28 (29 per cent) of the heifers with two or more positive cultures. Vaccination appeared to be curative because 44 per cent of vaccinated heifers were cleared of infection whereas 85 per cent of unvaccinated, inoculated heifers remained infected for at least 17 weeks. Vaccination improved the fertility level of the infected heifers threefold. Infection was not established in vaccinated bulls used for breeding infected heifers.

Bovine genital campylobacteriosis: isolation, identification and virulence profiling of Campylobacter fetus subsp. venerealis in a small animal model

“…After the first vaccination, 44.5% of bulls tested negative, with a total of 55.6% of animals negative after both vaccinations (Foscolo, Pellegrin et al 2005). Curative effect in heifers was similarly effective with 44% of vaccinated infected heifers clearing infection, compared to 15% of unvaccinated heifers, tested over 17 weeks (Eaglesome, Garcia et al 1986). Other farming practices include the use of dihydrostreptomycin intramuscular injections (22 mg/ kg body weight), which have been used concurrently with vaccination in infected bulls on artificial insemination studs successfully (n=17) (Garcia, Ruckerbauer et al 1983).…”

“…Vaccines for the prevention of BGC are available through different manufacturers in countries possessing large cattle production economies, such as Argentina (Vacuna anti Campylobacter Vaccination has also been used successfully as a curative in infected bulls (Foscolo, Pellegrin et al 2005) and heifers (Eaglesome, Garcia et al 1986). Twenty-seven bulls positive by direct fluorescent antibody testing (DFAT) were vaccinated twice, 23 days apart with an experimental vaccine.…”

Comparative aspects of immunity and vaccination in human and bovine trichomoniasis: a review

“…High infection clearance rates following vaccination mean that immunotherapy of valuable bulls is clinically feasible (Bondurant 2005). The same vaccine is used prophylactically to either prevent infection or significantly reduce the persistence of infection in both bulls and cows (Cobo et al 2011a, b;Bondurant 2005;Vasquez et al 1983;Eaglesome et al 1986;Corbeil et al 2003). In addition, immunized bulls do not become permanent carriers of Campylobacter foetus venerealis.…”

Campilobacteriose genital bovina e tricomonose genital bovina: epidemiologia, diagnóstico e controle

“…No caso de primovacinação, as novilhas e vacas devem receber duas doses, uma em torno de 60 e outra em torno de 30 dias antes do início da cobertura. O controle da CGB pelo emprego da vacinação em vacas é muito eficaz, mesmo em rebanhos que apresentam altas taxas de infecção (Clark et al 1974, Leite et al 1980, Eaglesome et al 1986, Ramos et al 1986. A relação custobenefício do controle da CGB empregando-se a vacinação das vacas é muito promissora, pois foi demonstrado que o retorno está próximo de 18 vezes os valores investidos na vacinação (Leite 1977).…”