Vaccinating rabbits against RVHD‐2

Saunders, Richard

doi:10.1136/vr.i384

Cited by 4 publications

(2 citation statements)

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“…It appears that there is shortly going to be a vaccine available in GB that can protect rabbits against RHDV‐2 (Saunders 2016). Implementing a routine vaccination programme that can fully protect against both variants should reduce the number of rabbit mortalities currently seen due to the RHDV‐2‐like variant.…”

Section: Figurementioning

confidence: 99%

Update on rabbit haemorrhagic disease virus 2‐like variant in Great Britain

McGowan

Choudhury

2016

Veterinary Record

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Section: Figurementioning

confidence: 99%

Update on rabbit haemorrhagic disease virus 2‐like variant in Great Britain

McGowan

Choudhury

2016

Veterinary Record

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“…Immunity against RHDV1 does not protect against RHDV2 (Le Gall-Reculé et al 2013, Peacock et al 2017 and deaths occurred in rabbits that were vaccinated against RHDV1 with Nobivac Myxo-RHD (MSD Animal Health), which was the only vaccine available in the UK at the outset of the RHDV2 epidemic. In 2016, adjuvanted inactivated vaccines against RHDV2, such as Eravac (Hipra Laboratories, Spain) and Filavac VHD K C + V (Filavie Laboratories, France) started to be imported (Saunders 2016) and, by 2018, both vaccines had product licences and were available in the UK.…”

Section: Introductionmentioning

confidence: 99%

RHDV2 epidemic in UK pet rabbits. Part 2: PCR results and correlation with vaccination status

Harcourt-Brown

Harcourt‐Brown

Joudou³

2020

J of Small Animal Practice

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To report PCR results and vaccination status of rabbits with rabbit haemorrhagic disease following an investigation into sudden or unexpected death. Materials and MethOds: PCR testing for RHDV2 and RHDV1 was performed on rabbit liver samples at two laboratories. Laboratory A reported results as positive or negative; Laboratory B reported results quantitatively as RNA copies per mg liver, categorised as negative, inconclusive or positive. The vaccination status of rabbits with both histopathological features of rabbit haemorrhagic disease and positive PCR test results were collated. results: PCR results matched histopathological findings in 188 of 195 (96%) cases. Seven individuals showed equivocal results, all of which had histopathological features of RHD but three tested PCRnegative and four results conflicted between laboratories. RHDV2 was the serotype detected in all PCR-positive cases. Histological features of rabbit haemorrhagic disease and PCR test results were positive in 125 rabbits; 51 unvaccinated, 56 in-date with Nobivac Myxo-RHD and 13 vaccinated against RHDV2-although nine of these were vaccinated within 10 days of death. clinical significance: PCR testing complements histopathology in cases of sudden death in rabbits by confirming the diagnosis and identifying virus serotype, but there can be false negatives. Although RHDV2 is currently prevalent in UK pet rabbits, vaccination against both RHDV1 and RHDV2 is recommended. Failures of RHDV2 vaccine are infrequent.

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Emerging Infectious Diseases of Rabbits

Gleeson

Petritz

2020

Veterinary Clinics of North America: Exotic Animal Practice

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Vaccinating rabbits against RVHD‐2

Cited by 4 publications

References 2 publications

Update on rabbit haemorrhagic disease virus 2‐like variant in Great Britain

Update on rabbit haemorrhagic disease virus 2‐like variant in Great Britain

RHDV2 epidemic in UK pet rabbits. Part 2: PCR results and correlation with vaccination status

Emerging Infectious Diseases of Rabbits

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