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Evgen'ev, M. I.; Garmonov, S. Yu.; Shakirova, L. Sh.

doi:10.1023/a:1016687826266

Cited by 15 publications

(7 citation statements)

References 99 publications

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“…The flow injection analysis (FIA) technique has also significantly contributed to automation advancement in pharmaceutical analysis. The basis of FIA is injecting a liquid sample into a nonsegmented moving, uninterrupted liquid carrier stream. − Analytical techniques including chromatographic, electrophoretic, electrochemical, spectroscopic, and titrimetric related processes for pharmaceutical analysis have been reviewed …”

Section: Analytical Techniques For the Estimation Of Pharmaceuticalsmentioning

confidence: 99%

Pharmaceuticals of Emerging Concern in Aquatic Systems: Chemistry, Occurrence, Effects, and Removal Methods

et al. 2019

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In the last few decades, pharmaceuticals, credited with saving millions of lives, have emerged as a new class of environmental contaminant. These compounds can have both chronic and acute harmful effects on natural flora and fauna. The presence of pharmaceutical contaminants in ground waters, surface waters (lakes, rivers, and streams), sea water, wastewater treatment plants (influents and effluents), soils, and sludges has been well doccumented. A range of methods including oxidation, photolysis, UV-degradation, nanofiltration, reverse osmosis, and adsorption has been used for their remediation from aqueous systems. Many methods have been commercially limited by toxic sludge generation, incomplete removal, high capital and operating costs, and the need for skilled operating and maintenance personnel. Adsorption technologies are a low-cost alternative, easily used in developing countries where there is a dearth of advanced technologies, skilled personnel, and available capital, and adsorption appears to be the most broadly feasible pharmaceutical removal method. Adsorption remediation methods are easily integrated with wastewater treatment plants (WWTPs). Herein, we have reviewed the literature (1990–2018) illustrating the rising environmental pharmaceutical contamination concerns as well as remediation efforts emphasizing adsorption.

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Section: Analytical Techniques For the Estimation Of Pharmaceuticalsmentioning

confidence: 99%

Pharmaceuticals of Emerging Concern in Aquatic Systems: Chemistry, Occurrence, Effects, and Removal Methods

et al. 2019

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“…The FIA technique has lent an important contribution to the development of automation in pharmaceutical analysis and its advantages are well documented in several review articles [53][54][55][56][57][58] as well as in a specialised monograph [59]. Despite the advantages presented and its relatively wide utilisation in research, its analytical applications in real situations did not have the expected acceptance.…”

Section: Sia Systems For Pharmaceutical Analysismentioning

confidence: 99%

Application of sequential injection analysis to pharmaceutical analysis

Pimenta

Montenegro

Araújo

et al. 2006

Journal of Pharmaceutical and Biomedical Analysis

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“…FIA became a versatile instrumental tool for the quality control of pharmaceuticals in the 21st century due to its instrumentation simplicity, inexpensive determination and high throughput capacities [5]. Pre-existing batch instruments can be easily converted to flow through by either home-made or commercially available cells [6].…”

Section: Introductionmentioning

confidence: 99%

Determination of N-Acetyl-l-cysteine Ethyl Ester (NACET) by Flow Injection Analysis and Spectrophotometric Detection Using Different Thiol-Sensitive Ligands

et al. 2021

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A new flow injection spectrophotometric method for the determination of N-acetyl-l-cysteine ethyl ester (NACET) was developed and validated. The method is based on the reduction of Cu(II)-ligand complexes to chromophoric Cu(I)-ligand complexes with the analyte. The studied ligands were neocuproine (NCN), bicinchoninic acid (BCA) and bathocuproine disulfonic acid (BCS). The absorbance of the Cu(I)-ligand complex was measured at 458, 562 and 483 nm for the reactions of NACET with NCN, BCA and BCS, respectively. The method was validated in terms of linear dynamic range, limit of detection and quantitation, accuracy, selectivity, and precision. Experimental conditions were optimized by a univariate method, yielding linear calibration curves in a concentration range from 2.0 × 10−6 mol L−1 to 2.0 × 10−4 mol L−1 using NCN; 2.0 × 10−6 mol L−1 to 1.0 × 10−4 mol L−1 using BCA and 6.0 × 10−7 mol L−1 to 1.2 × 10−4 mol L−1 using BCS. The achieved analytical frequency was 90 h−1 for all three ligands. The method was successfully employed for NACET determination in pharmaceutical preparations, indicating that this FIA method fulfilled all the essential demands for the determination of NACET in quality control laboratories, as it combined low instrument and reagent costs with a high sampling rate.

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Untitled

Cited by 15 publications

References 99 publications

Pharmaceuticals of Emerging Concern in Aquatic Systems: Chemistry, Occurrence, Effects, and Removal Methods

Pharmaceuticals of Emerging Concern in Aquatic Systems: Chemistry, Occurrence, Effects, and Removal Methods

Application of sequential injection analysis to pharmaceutical analysis

Determination of N-Acetyl-l-cysteine Ethyl Ester (NACET) by Flow Injection Analysis and Spectrophotometric Detection Using Different Thiol-Sensitive Ligands

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