Uveitis in dogs infected with Ehrlichia canis

Oriá, Arianne Pontes; Pereira, Patrícia Mendes; Laus, José Luiz

doi:10.1590/s0103-84782004000400055

Cited by 7 publications

(7 citation statements)

References 13 publications

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“…[ 21 ] reported a case with an antibody titer of 1:160. Castro [ 22 ] and Oria [ 23 ] used the IC test to determine IgG antibodies specific for the organism. Variable prevalence of ehrlichiosis has been reported from various parts of India.…”

Section: Discussionmentioning

confidence: 99%

Clinical and hematobiochemical response in canine monocytic ehrlichiosis seropositive dogs of Punjab

et al. 2017

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Aim:As in India especially, the Punjab state sero-prevalence and distribution of ehrlichiosis in relation to clinico-hematobiochemical response remains largely unexplored. Thus, this study was designed to determine the prevalence of vector (tick)-borne tropical canine pancytopenia caused by Ehrlichia canis through enzyme labeled ImmunoComb® (IC) assay in dogs from in and around Ludhiana, Punjab. Correlation of prevalence was made with various clinico-hematobiochemical parameters.Materials and Methods:Seroprevalence study was carried out using IC® test kit (Biogal, Galed Labs). The study was conducted in 84 dogs presented to the Small Animal Clinics, Teaching Veterinary Clinical Complex, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab.Results:Out of 84 suspected dogs for ehrlichiosis, based on peripheral thin blood smear examination 12 (14.28%) cases were positive for the morulae of E. canis and 73 (86.90%) dogs were found positive to E. canis antibodies through IC® canine Ehrlichia antibody test kit, respectively. Among the different age groups 1-3 years of aged group showed highest prevalence (41.09%), followed by the 3-6 years age group (32.87%), infection levels were lower in the <1 year of age group dogs (13.69%) and more than 6 years age group dogs (12.32%). The highest prevalence was seen in Labrador retriever. This study indicates that season plays a very important role in the prevalence of ehrlichiosis. The most common findings observed were anemia, leukocytosis, neutropenia, lymphopenia, thrombocytopenia, eosinophilia followed by hyperbilirubinemia, increased levels of aspartate aminotransferase, alanine aminotransferase and alkaline phosphatase, hypoalbuminemia, hyperglobulinaemia, decrease in albumin and globulin ratio, increase in blood urea nitrogen and creatinine.Conclusions:Serological techniques like IC® are more useful for detecting chronic and subclinical infections and are ideally suited to epidemiological investigations.

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Section: Discussionmentioning

confidence: 99%

Clinical and hematobiochemical response in canine monocytic ehrlichiosis seropositive dogs of Punjab

et al. 2017

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“…Hallazgos del fondo de ojo, cámara anterior y vítreo en el presente estudio corroboran los postulados de la uveítis como manifestación ocular de infección sistémica por E. canis (Oriá et al, 2004). Se destaca que el 46% de los caninos presentaron edema perivascular, hemorragia y desprendimiento, neuritis óptica y vasos retinianos tortuosos; asimismo, el 30% presentaron fondo y vítreo normal y en el 50% de los pacientes no fue posible observarlo.…”

Section: Resultados Y Discusiónunclassified

Hallazgos oculares como factores predictivos y diagnósticos de erlichiosis canina

Piso¹,

Ramírez

Padilla³

et al. 2019

Rev. investig. vet. Perú

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El objetivo del presente estudio fue determinar la posibilidad de predecir infecciones por Ehrlichia canis con base a lesiones oculares de caninos sin signos clínicos sistémicos aparentes sugerentes de infección por Erlichia. Se trabajó con 30 caninos llevados a la Clínica Veterinaria de la Universidad Cooperativa de Colombia (Ibagué) por alteraciones oculares. Se realizó el examen oftálmico completo. Aquellos con uveítis o hemorragias retinianas se les realizó el SNAP test para Ehrlichia canis. El principal motivo de consulta oftálmico de los pacientes positivos a E. canis fue secreción ocular (33.3%), seguido ojo rojo (30%) y de pérdida de la visión (20%). Al examen oftálmico, la alteración ocular más frecuentemente fue disminución de la presión intraocular (PIO) (93.3%) e hiperemia conjuntival (63.3%). El 46.7% presentó aumento de la secreción ocular y el 40% fue positivo a queratoconjuntivitis seca (KCS) (Rosa de Bengala +). Desprendimiento de retina y edema perivascular de vasos retinianos fue encontrado en el 26.7% de los pacientes. En conclusión, el ojo rojo, PIO baja y la KCS de tipo cualitativo se presentan como hallazgos tempranos de la ehrlichiosis canina; por tanto, estos signos deberían ser considerados como sugerentes de la enfermedad en regiones endémicas.

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“…Such a finding may be due to intensification of aqueous humor drainage via the uveal-scleral pathway and/or reduction of the production of aqueous humor by the inflamed ciliary body. With the chronicity of the disease, this compensatory pathway tends to become unbalanced to such an extent that the IOP exceeds the normal values (ORIÁ et al, 2004;PLUMMER et al, 2013).…”

Section: Discussionmentioning

confidence: 99%

Molecular diagnosis of Ehrlichia canis infection in dogs with uveitis

Veloso

Sauer

Oriá

et al. 2018

SCA

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Canine monocytic ehrlichiosis (CME) is an infectious disease caused by a gram-negative bacterium Ehrlichia canis that has a high global prevalence that leads to high rates of morbidity and mortality in dogs. Among the clinical changes, ophthalmic diseases can lead to permanent blindness and it can be an important clinical sign. The objective of this study was to perform nested polymerase chain reaction (PCR) to diagnose E. canis infection in dogs with bilateral uveitis from the Veterinary Hospital of the Santa Cruz State University. Blood samples were collected and DNA for the molecular diagnosis was extracted from 66 adult dogs of both genders and mixed breeds diagnosed with bilateral uveitis. Thirtyfive (53%) dogs showed positive results and presented with iridocyclitis, posterior uveitis, panuveitis, or uveitis with secondary glaucoma. This study demonstrates that nested PCR is an important tool for the differential diagnosis of dogs with bilateral uveitis, as it provides evidence of the infectious agent in the animal. Key words: Eye. Glaucoma. Infectious Uveitis. Nested PCR. Rickettsia. ResumoErliquiose Monocítica Canina (EMC) é uma doença infecciosa causada por uma bactéria gram negativa da espécie Ehrlichia canis, que possui alta prevalência mundial e conduz a elevadas taxas de morbidade e mortalidade em cães. Dentre as alterações clínicas, as oftalmopatias podem levar a cegueira permanente e é ser um importante sinal clínico. Objetivou-se realizar nested-PCR para diagnosticar infecção por E. canis em cães portadores de uveíte bilateral provenientes da casuística do Hospital Veterinário da Universidade Estadual de Santa Cruz. Sessenta e seis cães adultos, de ambos sexos e raças variadas, diagnosticados com uveíte bilateral foram submetidos a coleta de sangue e o DNA para realização do diagnóstico molecular foi extraído destas amostras. Foram positivos no teste 35 (53%) cães, que apresentaram iridociclite, uveíte posterior, panuveíte ou uveíte com glaucoma secundário. Esse estudo demonstra a nested-PCR como ferramenta importante no diagnóstico diferencial de cães com uveíte

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Uveitis in dogs infected with Ehrlichia canis

Cited by 7 publications

References 13 publications

Clinical and hematobiochemical response in canine monocytic ehrlichiosis seropositive dogs of Punjab

Clinical and hematobiochemical response in canine monocytic ehrlichiosis seropositive dogs of Punjab

Hallazgos oculares como factores predictivos y diagnósticos de erlichiosis canina

Molecular diagnosis of Ehrlichia canis infection in dogs with uveitis

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