Uso de concentrados autólogos de plaquetas intraarticulares como coadyuvantes en el tratamiento quirúrgico de la rotura del ligamento cruzado anterior en una perra

Abstract

SUMMARYCranial cruciate ligament rupture (CCLR) is one of the main orthopedic problems that could produce hind limb lameness in dogs. Even though this problem can be surgically treated the development and progression of osteoarthritis are typical features. A case of a dog that received postoperative intra-articular injections of autologous platelet concentrates (APCs) after the surgical reparation of a CCLR is described. The clinical, radiographic, and gait analysis results could potentially support the postoperative use of intra-articular injections of APCs as an adjunctive therapy in the CCLR surgical reparation.Palabras clave: perro, rotura del ligamento cruzado anterior, plasma rico en plaquetas, terapia regenerativa.

Intra-Articular Autologous Platelet Concentrate (APC) in the Treatment of Induced Knee Osteoarthritis (OA) in Rabbits — An Arthroscopic Evaluation

“…[64,65] It is therefore a way to track in vivo evolution of articular processes and their treatment. The limitations in second arthroscopic evaluation in clinical practice and the diversity of clinical situations [13,16,28,29] indicate the need for research that continuously assesses the process and treatment, as was performed in the first stage of this study. One of the difficulties encountered in this experimental model was the minimum quantity of synovial fluid in healthy joints, that is, 0.1 to 0.2 mL, which prevented the evaluation of the parameters.…”

“…The method used was the same standard as used in previous studies. [13,29] The early diagnosis of joint injury is undoubtedly an important factor in controlling subsequent degenerative lesions, but this is not the clinical reality. Therefore, other forms of controlling or even inhibiting the degenerative process should be investigated.…”

“…[13] There are different ways to obtain APC. [48][49][50] It can be prepared by automated methods, semi-automated methods, or the simplest way, that is, the tube method with single [13,29,51] or double centrifugation. [42] The most important method to prepare platelet concentrate is to ensure that in addition to concentrating a high number of platelets, it allows for obtaining live and inactivated platelets.…”

“…Despite the lack of the standardization of the techniques employed, the literature reports promising clinical results in humans [22][23][24], horses [25][26][27], and dogs. [13,16,28,29] Clinical studies have shown early recovery and pain relief, as observed in the evaluation of dogs after receiving treatment for a rupture of the cranial cruciate ligament [13,29] and the fragmented coronoid process. [13,28,29] Because APC stimulates the healing of tissue, it has been used to treat different joint injuries, such as osteoarthritis, osteochondrosis, hip and elbow dysplasia, chondral defects, tendinitis, bursitis, menisci injuries, muscle injuries, wounds, and fractures, and it has been used as an adjunct in the treatment of the rupture of the cruciate ligament.…”

“…[13,16,28,29] Clinical studies have shown early recovery and pain relief, as observed in the evaluation of dogs after receiving treatment for a rupture of the cranial cruciate ligament [13,29] and the fragmented coronoid process. [13,28,29] Because APC stimulates the healing of tissue, it has been used to treat different joint injuries, such as osteoarthritis, osteochondrosis, hip and elbow dysplasia, chondral defects, tendinitis, bursitis, menisci injuries, muscle injuries, wounds, and fractures, and it has been used as an adjunct in the treatment of the rupture of the cruciate ligament. [22,16,28,29,25,30,18,31,32] The results may vary depending on the severity of the case [33] and the method for obtaining the APC.…”