Use of the Scintillation Anger Camera and Xenon Xe 133 in the Study of Chronic Obstructive Lung Disease

Medina, Jose R.; Lillehei, James P.; Loken, Merle K.; Ebert, Richard V.

doi:10.1001/jama.1969.03160060055005

Cited by 15 publications

(2 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We propose as an explanation that in these patients quasi unventilated areas are present during the single breath test (areas with very large time constants), which did not receive enough inspired gas to affect the single breath plateau significantly, and therefore could not be corrected on the basis of the phase III slope. These lung regions are more or less ventilated during rebreathing, 25 To describe the single breath phase III for argon a changing distribution of ventilation in the A and A' compartments as a function of inspired (I) or expired (E) volume was imposed according to the following equations:…”

Section: Relation With Maldistribution Of Ventilationmentioning

confidence: 99%

A simple method for correcting single breath total lung capacity for underestimation.

Loiseau

Loiseau²,

Saumon³

1990

Thorax

View full text Add to dashboard Cite

The single breath method underestimates total lung capacity by comparison with the multiple breath method (TLCmb) because of inhomogeneity of ventilation distribution. This study proposes a simple correction for the single breath TLC (TLCsb), using inert gas phase III slope to account for the effects of uneven ventilation distribution. A model of a non-uniform lung ventilation was designed, composed of a serial dead space and two alveolar compartments arranged in parallel,

show abstract

Section: Relation With Maldistribution Of Ventilationmentioning

confidence: 99%

A simple method for correcting single breath total lung capacity for underestimation.

Loiseau

Loiseau²,

Saumon³

1990

Thorax

View full text Add to dashboard Cite

show abstract

“…This can be done either separately or using 133xenon for ventilation studies followed by macroaggregates, or xenon can be injected intravenously during breath holding, thus giving a record of perfusion, since the gas is liberated FIG 13 b, c, d. in the alveoli in proportion to their blood flow. The subsequent wash-out of this gas from the alveoli can be used as a measure of regional ventilation (Farmelant & Trainor, 1971;Medina et al, 1969).…”

Section: Chronic Lung Diseasementioning

confidence: 99%

Radioisotope scanning of brain, liver, lung and bone with a note on tumour localizing agents

Lavender

1973

Postgraduate Medical Journal

View full text Add to dashboard Cite

SummaryRadioisotopic scanning of brain, liver, lungs and the skeleton is briefly reviewed with a survey of recent developments of clinical significance. In brain scanning neoplasm detection rates of greater than 90%O are claimed. The true figure is probably 70-80%. Autopsy data shows a number of false negatives, particularly with vascular lesions. Attempts to make scanning more specific in differentiating neoplasm from vascular lesions by rapid sequence blood flow studies are reviewed.In liver scanning by means of colloids again high success rate is claimed but small metastases are frequently missed and the false negative scan rate is probably quite high.Lung scanning still has its main place in investigating pulmonary embolic disease. Ventilation studies using Xenon 133 are useful, particularly combined with perfusion studies.The various radiopharmaceuticals for use in bone scanning are reviewed. The appearance of technetium labelled phosphate compounds will probably allow much wider use of total skeletal scanning.Research into tumour localizing agents continues, the most recent and interesting being Gallium citrate and labelled bleomycin. Neither agent is predictable however although Gallium may have a place in Hodgkins disease and bronchogenic neoplasm and both may have a place in the detection of cerebral tumours. IntroductionThis brief review is intended to look at some of the more common applications of radioisotope scanning, and also at certain new developments, in their clinical setting. Recent changes in detecting apparatus and in radiopharmaceuticals are widening the scope of scanning procedures, making investigations more specific; this outline may indicate the type of information and the order of accuracy that can be expected from the various investigations covered.

show abstract

Quantitative comparison of 99mTc-iron hydroxide aggregates and 133Xe pulmonary perfusion, and importance of sensitivity-corrected gamma-camera data

Brookeman

1974

The International Journal of Applied Radiation and Isotopes

View full text Add to dashboard Cite

Use of the Scintillation Anger Camera and Xenon Xe 133 in the Study of Chronic Obstructive Lung Disease

Cited by 15 publications

References 7 publications

A simple method for correcting single breath total lung capacity for underestimation.

A simple method for correcting single breath total lung capacity for underestimation.

Radioisotope scanning of brain, liver, lung and bone with a note on tumour localizing agents

Quantitative comparison of 99mTc-iron hydroxide aggregates and 133Xe pulmonary perfusion, and importance of sensitivity-corrected gamma-camera data

Contact Info

Product

Resources

About