Use of substances of animal origin in pharmaceutics and compliance with the TSE-risk guideline – a market survey

Berger, Christoph; Donne, Patrizia Le; Windemann, Helena

doi:10.1016/j.biologicals.2004.10.002

Cited by 9 publications

(8 citation statements)

References 3 publications

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“…Moreover, there is risk of infection with various pathogens and diseases are involved from the use of animal-derived substances in drug manufacturing. Therefore, the efforts of the drug manufacturer to correspond to regulatory actions and to implement authoritative guidelines should be improved [55].…”

Section: Sulfamerazine -Nada 033-950mentioning

confidence: 99%

Aquaculture Drugs: Sources, Active Ingredients, Pharmaceutic Preparations and Methods of Administration

Kumar¹,

Roy²

2017

J Aquac Res Development

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Section: Sulfamerazine -Nada 033-950mentioning

confidence: 99%

Aquaculture Drugs: Sources, Active Ingredients, Pharmaceutic Preparations and Methods of Administration

Kumar¹,

Roy²

2017

J Aquac Res Development

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“…Today, animal-derived ingredients are less frequently used for various reasons [5]. They include the infectious risk of some derivatives, but also ethical issues (animal cruelty) and concerns regarding the protection of biodiversity and endangered species, such as whales and turtles [6,7].…”

Section: Introductionmentioning

confidence: 99%

Zooceuticals and Cosmetic Ingredients Derived from Animals

Cristiano¹,

Guagni²

2022

Cosmetics

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Many substances derived from animals are used as ingredients in the cosmetic industry and constitute a particular type of product: zooceuticals. The main ingredients used can come from insects, such as snail slime; land animals, such as lanolin; and marine animals, such as marine collagen. Today, they are used less than in the past for hygienic–sanitary, ethical, and ecological reasons. Moreover, some can give rise to irritative or allergic dermatitis. However, they still represent a fraction of the common ingredients in certain types of cosmetic products today.

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“…Although, the safety evaluations of animal origin material are also included, and the risk might be significantly low, the risk cannot be completely removed unless animal-origin materials are used. [22][23][24][25] γ-Polyglutamic acid (PGA) is a non-animal origin biodegradable polyamino acid, which is known as a sticky paste formed on the surface of fermented soybeans, "Natto". Since PGA is a low-cost, non-toxic, water-retentive material, it has been applied as a material in various fields, such as cosmetics, food, plastics and a flocculant for water treatment.…”

Section: Introductionmentioning

confidence: 99%

Fabrication of an Implantable Fine Needle-Type Glucose Sensor Using γ-Polyglutamic Acid

Takaoka

Yasuzawa

2010

ANAL. SCI.

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Implantable fine needle-type glucose sensors with an outer diameter of less that 0.2 mm were fabricated using a low-cost and non-animal origin polyamide, gamma-polyglutamic acid (PGA) as a glucose oxidase (GOx) immobilizing material. Two types of PGA, gamma-polyglutamic acid (PGAH) and gamma-polyglutamic acid sodium salt (PGANa), were employed to prepare GOx immobilized film by the covalent attachment of GOx using water-soluble carbodiimide (EDC). Nafion/cellulose acetate composite film and polyurethane/polydimethylsiloxane composite film were employed as a permselective inner film and a biocompatible outer film, respectively. The procedure of enzyme-immobilized film fabrication affected the stability of the sensor; that is, GOx immobilized film prepared by pouring a mixture solution of GOx and EDC on a PGA precoated surface showed higher sensor stability than that prepared by pouring a mixture solution of GOx, PGA and EDC. Although, obvious differences in the sensor properties were not observed between the use of PGANa and PGAH, the electrode prepared with PGAH had a lower swelling degree. The glucose sensors prepared with both PGANa and PGAH were practically not affected by the existence of electroactive compounds, such as uric acid, and provided long-term stability for approximately 5 weeks. These sensors also showed good performance in horse serum.

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Use of substances of animal origin in pharmaceutics and compliance with the TSE-risk guideline – a market survey

Cited by 9 publications

References 3 publications

Aquaculture Drugs: Sources, Active Ingredients, Pharmaceutic Preparations and Methods of Administration

Aquaculture Drugs: Sources, Active Ingredients, Pharmaceutic Preparations and Methods of Administration

Zooceuticals and Cosmetic Ingredients Derived from Animals

Fabrication of an Implantable Fine Needle-Type Glucose Sensor Using γ-Polyglutamic Acid

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