Use of small volume hypertonic acetate dextran during aortic occlusion in pigs: assessment of blood flow and antioxidant status in tissues

Cardiovascular effects of shock and trauma in experimental models. A review

“…It is obvious that adenosine and Mg may have been instrumental in this response; the role played by lidocaine requires further investigation. Dubick et al [ 46 ] report that hypertonic acetate resuscitation from aortic cross-clamping offered only minor advantages over hypertonic bicarbonate in terms of blood flow and anti-oxidant status. This observation should be coupled with a previously reported one [ 1 ] showing that hypertonic acetate induces significant pulmonary vasoconstriction.…”